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CHEK1 抗体 (pSer345)

This anti-CHEK1 antibody is a 兔 多克隆 antibody detecting CHEK1 in WB. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN232760
发货至: 中国

Quick Overview for CHEK1 抗体 (pSer345) (ABIN232760)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This CHEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pSer345

    特异性

    Detects endogenous levels of Chk1 only when activated by phosphorylation at serine 345. Does not recognize Chk1 phosphorylated at other sites. Species cross-reactivity: Monkey, mouse and rat.

    纯化方法

    Protein A purified

    免疫原

    Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser345 of human Chk1.

    Type of Immunogen: Synthetic phospho-peptide

    亚型

    IgG
  • 应用备注

    Approved: WB (1:1000)

    Usage: Western Blot: 1:1000, incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4?C with gentle shaking, overnight. Flow Cytometry: 1:50.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

    储存液

    Without preservative

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    CHEK1 / CHK1

    背景

    Name/Gene ID: CHEK1
    Subfamily: NIM1
    Family: Protein Kinase

    Synonyms: CHEK1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase 1, CHK1, Chk1-S, Protein kinase chk1, Checkpoint kinase-1

    基因ID

    1111

    UniProt

    O14757

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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