Aurora Kinase B 抗体 (AA 227-238)
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- 抗原 See all Aurora Kinase B (AURKB) 抗体
- Aurora Kinase B (AURKB)
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抗原表位
- AA 227-238
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aurora Kinase B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Detects Aurora-B kinase (AurB), a serine/threonine kinase which is the enzymatic core of the Chromosomal Passenger Complex (CPC). This complex functions in chromosome alignment and separation, histone modification, and cytokinesis. CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB. Two CPCs exist during mitosis- one containing all four members, and another consisting of INCENP and AurB. Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3. AurB is overexpressed in a number of tumors, including primary breast and colon tumor samples. Its expression in tumors seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.
- 纯化方法
- Purified
- 免疫原
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Synthetic peptide corresponding to amino acids 227-238 of human Aurora-B kinase.
Type of Immunogen: Synthetic peptide - 亚型
- IgG
- Top Product
- Discover our top product AURKB Primary Antibody
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anti-Aurora Kinase B (AURKB) (AA 223-234), (pThr232) antibody
AURKB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) (AA 1-90) antibodyAURKB 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 6H7 unconjugated
anti-Aurora Kinase B (AURKB) (AA 6-35) antibodyAURKB 适用: 人, 小鼠, 大鼠, 灵长类 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) antibodyAURKB 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 4E5 unconjugated Recombinant Antibody
anti-Aurora Kinase B (AURKB) (AA 89-251) antibodyAURKB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rAURKB-1592 unconjugated Recombinant Antibody
anti-Aurora Kinase B (AURKB) (AA 1-90) antibodyAURKB 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6G8 unconjugated
anti-Aurora Kinase B (AURKB) (pThr232) antibodyAURKB 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) (AA 1-255) antibodyAURKB 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) (AA 89-251) antibodyAURKB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal AURKB-1592 unconjugated
anti-Aurora Kinase B (AURKB) (pThr232) antibodyAURKB 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Approved: ELISA (1:2000 - 1:10000), WB (1:250 - 1:1000)
Usage: Western Blot: LS-C42572 detects a band of approximately 39kD in HeLa cell lysates. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.2, 0.01 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- Aurora Kinase B (AURKB)
- 别名
- AURKB / Aurora-B (AURKB 产品)
- 别名
- AIK2 antibody, AIM-1 antibody, AIM1 antibody, ARK2 antibody, AurB antibody, IPL1 antibody, PPP1R48 antibody, STK12 antibody, STK5 antibody, aurkb-sv1 antibody, aurkb-sv2 antibody, AIRK2 antibody, AL022959 antibody, Aik2 antibody, Aim1 antibody, Ark2 antibody, STK-1 antibody, Stk12 antibody, Stk5 antibody, Aur B antibody, Aurora B antibody, Aurora-B antibody, CG6620 antibody, DmAIRK2 antibody, DmAurB antibody, DmAuroraB antibody, Dmel\\CG6620 antibody, IAL antibody, IAL1 antibody, Ial antibody, aurB antibody, aurora B antibody, ARK-2 antibody, XAIRK2 antibody, aik2 antibody, aim-1 antibody, aim1 antibody, airk2 antibody, ark2 antibody, ipl1 antibody, stk12 antibody, stk5 antibody, CHUNP6896 antibody, fa09g06 antibody, stka antibody, wu:fa09g06 antibody, aurkb antibody, AIRK2-B antibody, XAIRK2-B antibody, aurkb-a antibody, aurkb-b antibody, xAurora-B-B antibody, aurora kinase B antibody, aurora B antibody, aurora kinase B S homeolog antibody, AURKB antibody, Aurkb antibody, aurB antibody, aurkb antibody, aurkb.S antibody
- 背景
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Name/Gene ID: AURKB
Subfamily: Aurora/IPL1-like
Family: Protein Kinase
Synonyms: AURKB, AIRK2, AIK2, Aurora kinase B, Aurora kinase B-Sv1, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, ARK-2, ARK2, Aurkb-sv1, Aurkb-sv2, Aurora 1, Aurora-B, AIM-1, IPL1, STK-1, STK5, PPP1R48, AurB, Aurora B, Aurora kinase B-Sv2, Aurora-1, Aurora1, Serine/threonine kinase 12, STK1, STK12 - 基因ID
- 9212
- UniProt
- Q96GD4
- 途径
- TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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