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Aurora Kinase B 产品

(Aurora Kinase B (AURKB))

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This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013].

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Featured Aurora Kinase B Categories

Aurora Kinase B 抗体

High quality antibodies with extensive validation data.

Aurora Kinase B ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Aurora Kinase B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Aurora Kinase B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (18)
  • (4)
Cat. No. ABIN129612
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IP
Validations
  • (5)
Cat. No. ABIN563978
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Primate, Rat
Application WB, ELISA, IHC
Validations
  • (6)
Cat. No. ABIN3030076
Quantity 0.4 mL
Datasheet Datasheet

Recommended Aurora Kinase B ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954015
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380441
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended Aurora Kinase B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5569617
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5569845
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346213
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Aurora Kinase B Products

Barroso-Vilares, Macedo, Reis, Warren, Compton, Logarinho: "Small-molecule inhibition of aging-associated chromosomal instability delays cellular senescence." in: EMBO reports, Vol. 21, Issue 5, pp. e49248, (2020) (PubMed).

Achuthankutty, Thakur, Haahr, Hoffmann, Drainas, Bizard, Weischenfeldt, Hickson, Mailand: "Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability." in: The Journal of cell biology, Vol. 218, Issue 12, pp. 3943-3953, (2020) (PubMed).

Novais-Cruz, Alba Abad, van IJcken, Galjart, Jeyaprakash, Maiato, Ferrás: "Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription." in: eLife, Vol. 7, (2019) (PubMed).

Liu, Kwon, Mannino, Yang, Renda, Khodjakov, Pellman: "Nuclear envelope assembly defects link mitotic errors to chromothripsis." in: Nature, Vol. 561, Issue 7724, pp. 551-555, (2019) (PubMed).

Fang, Niu, Mo, Zhu, Tan, Wei, Li, Chen, Yang, Balajee, Zhao: "RecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrity." in: Oncogenesis, Vol. 7, Issue 9, pp. 68, (2018) (PubMed).

Xie, Lin, Wu, Tan, Cheng, Zhang: "Cardiac glycoside bufalin blocks cancer cell growth by inhibition of Aurora A and Aurora B activation via PI3K-Akt pathway." in: Oncotarget, Vol. 9, Issue 17, pp. 13783-13795, (2018) (PubMed).

Skowyra, Allan, Saurin, Clarke: "USP9X Limits Mitotic Checkpoint Complex Turnover to Strengthen the Spindle Assembly Checkpoint and Guard against Chromosomal Instability." in: Cell reports, Vol. 23, Issue 3, pp. 852-865, (2018) (PubMed).

Drpic, Almeida, Aguiar, Renda, Damas, Lewin, Larkin, Khodjakov, Maiato: "Chromosome Segregation Is Biased by Kinetochore Size." in: Current biology : CB, Vol. 28, Issue 9, pp. 1344-1356.e5, (2018) (PubMed).

de Cárcer, Venkateswaran, Salgueiro, El Bakkali, Somogyi, Rowald, Montañés, Sanclemente, Escobar, de Martino, McGranahan, Malumbres, Sotillo: "Plk1 overexpression induces chromosomal instability and suppresses tumor development." in: Nature communications, Vol. 9, Issue 1, pp. 3012, (2018) (PubMed).

Dumitru, Rusin, Clark, Kettenbach, Compton: "Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability." in: eLife, Vol. 6, (2017) (PubMed).

Synonyms and alternative names related to Aurora Kinase B

aurora kinase B (AURKB), aurora kinase B (Aurkb), aurora B (aurB), aurora kinase B (aurkb), aurora kinase B S homeolog (aurkb.S), AIK2, Aik2, aik2, AIM-1, aim-1, AIM1, Aim1, aim1, AIRK2, airk2, AIRK2-B, AL022959, ARK-2, ARK2, Ark2, ark2, AurB, Aur B, aurB, aurkb, aurkb-a, aurkb-b, aurkb-sv1, aurkb-sv2, Aurora-B, Aurora B, aurora B, CG6620, CHUNP6896, DmAIRK2, DmAurB, DmAuroraB, Dmel\\CG6620, fa09g06, IAL, Ial, IAL1, IPL1, ipl1, PPP1R48, STK-1, STK5, Stk5, stk5, STK12, Stk12, stk12, stka, wu:fa09g06, XAIRK2, XAIRK2-B, xAurora-B-B

Protein level used designations for Aurora Kinase B

  • ARK-2
  • STK-1
  • aurora 1
  • aurora kinase B-Sv1
  • aurora kinase B-Sv2
  • aurora- and Ipl1-like midbody-associated protein 1
  • aurora-1
  • aurora-B
  • aurora-related kinase 2
  • aurora/IPL1-related kinase 2
  • protein phosphatase 1, regulatory subunit 48
  • serine/threonine kinase 12
  • serine/threonine-protein kinase 12
  • serine/threonine-protein kinase 5
  • serine/threonine-protein kinase aurora-B
  • aurora B
  • aurora- and IPL1-like midbody-associated protein 1
  • serine/threonine kinase 5
  • AURORA-like
  • CG6620-PA
  • DmAuroraB
  • aurora
  • aurora B kinase
  • auroraB
  • dAurora B
  • ial-PA
  • AIM-1
  • Serine/threonine-protein kinase 12
  • xAurora-B
  • aurB
  • cei
  • cellular island
  • serine/threonine kinase a
  • aurora kinase B
  • serine/threonine-protein kinase 12-like
  • Aurora/IPL1-related kinase 2-B
  • Serine/threonine-protein kinase 12-B
  • Serine/threonine-protein kinase aurora-B-B
  • aurora kinase B-B
  • aurora-B-B
  • aurora/IPL1-related kinase 2-B
  • serine/threonine-protein kinase 12-B
  • serine/threonine-protein kinase aurora-B-B
  • xAurora-B-B
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