Vinexin 抗体 (AA 401-500) (AbBy Fluor® 488)
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- 抗原 See all Vinexin (Sorbs3) 抗体
- Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))
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抗原表位
- AA 401-500
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Vinexin antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Vinexin
- 亚型
- IgG
- Top Product
- Discover our top product Sorbs3 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))
- 别名
- Vinexin (Sorbs3 产品)
- 别名
- zgc:113031 antibody, si:dkey-162f21.1 antibody, SCAM-1 antibody, SH3P3 antibody, Sh3d4 antibody, vinexin-g antibody, SCAM1 antibody, SH3D4 antibody, sorbin and SH3 domain containing 3 antibody, SORBS3 antibody, sorbs3 antibody, Sorbs3 antibody
- 背景
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Synonyms: SCAM 1, SCAM1, SH3 containing adapter molecule 1, SH3 domain containing adapter molecule 1, SH3D4, Sorbin and SH3 domain containing 3, Sorbin and SH3 domain containing protein 3, Sorbs3, Vinexin alpha, Vinexin, Vinexin beta (SH3 containing adaptor molecule 1).
Background: Vinexin is a 671 amino acid protein that is expressed as two isoforms, designated Vinexin alpha and Vinexin beta. Localized to cell junctions in both the cytoplasm and the cytoskeleton, Vinexin alpha functions to promote Actin stress fiber formation, playing an important role in modification of the Actin cytoskeleton. Like Vinexin alpha, Vinexin beta is localized to cell junctions in the cytoplasm, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation. Although Vinexin alpha and Vinexin beta have different roles within the cell, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, including placenta, heart, liver, brain, pancreas and skeletal muscle. Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, signal transduction and cytoskeletal organization throughout the cell.
- 途径
- MAPK Pathway
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