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Vinexin 抗体 (AA 401-500)

Sorbs3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2180071
发货至: 中国
  • 抗原 See all Vinexin (Sorbs3) 抗体
    Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))
    抗原表位
    • 14
    • 7
    • 1
    AA 401-500
    适用
    • 23
    • 2
    • 2
    宿主
    • 23
    • 2
    克隆类型
    • 25
    多克隆
    标记
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Vinexin antibody is un-conjugated
    应用范围
    • 21
    • 12
    • 12
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Vinexin
    亚型
    IgG
    Top Product
    Discover our top product Sorbs3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))
    别名
    Vinexin (Sorbs3 产品)
    别名
    zgc:113031 antibody, si:dkey-162f21.1 antibody, SCAM-1 antibody, SH3P3 antibody, Sh3d4 antibody, vinexin-g antibody, SCAM1 antibody, SH3D4 antibody, sorbin and SH3 domain containing 3 antibody, SORBS3 antibody, sorbs3 antibody, Sorbs3 antibody
    背景

    Synonyms: SCAM 1, SCAM1, SH3 containing adapter molecule 1, SH3 domain containing adapter molecule 1, SH3D4, Sorbin and SH3 domain containing 3, Sorbin and SH3 domain containing protein 3, Sorbs3, Vinexin alpha, Vinexin, Vinexin beta (SH3 containing adaptor molecule 1).

    Background: Vinexin is a 671 amino acid protein that is expressed as two isoforms, designated Vinexin alpha and Vinexin beta. Localized to cell junctions in both the cytoplasm and the cytoskeleton, Vinexin alpha functions to promote Actin stress fiber formation, playing an important role in modification of the Actin cytoskeleton. Like Vinexin alpha, Vinexin beta is localized to cell junctions in the cytoplasm, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation. Although Vinexin alpha and Vinexin beta have different roles within the cell, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, including placenta, heart, liver, brain, pancreas and skeletal muscle. Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, signal transduction and cytoskeletal organization throughout the cell.

    途径
    MAPK Pathway
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