MAP2K3 抗体 (pSer207)
Quick Overview for MAP2K3 抗体 (pSer207) (ABIN2177687)
抗原
See all MAP2K3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer207
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特异性
- This phosphorylation site is homologous in Mouse and homologous to that of Ser290 in Rat in MKK3, and homologous across the listed species in MKK6.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human MKK3 around the phosphorylation site of Ser218
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-170) antibody
MAP2K3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5C7 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 小鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5D3 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-138) antibodyMAP2K3 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E12D11 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-100) antibodyMAP2K3 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5F2 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (pSer189) antibodyMAP2K3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 15-45), (N-Term) antibodyMAP2K3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0928 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (pSer189) antibodyMAP2K3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B5 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
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别名
- MKK3 + MKK6
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背景
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Synonyms: MKK3Ser218, MAP Kinase Kinase 3, Dual specicity mitogen activated protein kinase kinase 3, ERK kinase 3, MAP kinase kinase 3, MAP2K 3, MAPK ERK kinase 3, MAPK kinase 3, MAPKK 3, MAPKK3, MEK 3, MEK3, Mitogen activated protein kinase kinase 3, MKK 3, MKK3, mMKK 3b, mMKK3b, MPK 3, PRKMK 3, PRKMK3, Protein kinase mitogen activated kinase 3, SKK2, zMKK 3, MP2K3_HUMAN, MP2K6_HUMAN
Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.
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基因ID
- 5606, 5608
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途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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