IL-6 抗体
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北京 101111
Quick Overview for IL-6 抗体 (ABIN217588)
抗原
See all IL-6 (IL6) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes chicken Interleukin 6 (chIL-6). Mammalian IL-6 is a multifunctional pro-inflammatory cytokine, which plays a major role in the regulation of immune responses, haematopoiesis and the induction of acute phase responses. The action of IL-6 occurs via the signal transducing receptor chain gp130 and the IL-6 receptor alpha chain is responsible for ligand binding. IL-6 is produced by a wide variety of cells including B lymphocytes, T lymphocytes, monocytes/macrophages, fibroblasts and endothelial cells and has a widespread cellular effect, including B and T lymphocytes, hepatocytes and cells of the CNS. Chicken hepatocyte-stimulating factor (HSF), secreted by lipopolysaccharide (LPS)-stimulated macrophages, induces fibronectin production in cultured chicken hepatocytes, and that HSF produced by LPS-treated fibroblasts, was neutralized by an antiserum to recombinant HuIL-6 (rHuIL-6). rHuIL-6 has also been shown as biologically active on chicken hepatocytes (Samad et al. 1993).(AHP942Z) neutralizes chicken IL-6 in the murine7TD1 IL-6 bioassay.
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纯化方法
- Affinity purified
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免疫原
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Recombinant chicken IL-6.
Type of Immunogen: Recombinant protein -
亚型
- IgG
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应用备注
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Approved: ELISA, Func, WB
Usage: Western Blot: LS-C43117 detects a band of approximately 27kD. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. -
说明
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Target Species of Antibody: Chicken
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS.
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- IL-6 (IL6) (Interleukin 6 (IL6))
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别名
- IL6
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背景
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Name/Gene ID: IL6
Family: Hormone
Synonyms: IL6, B-cell stimulatory factor 2, BSF-2, BSF2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, Interleukin-6, Interferon beta-2, Interleukin BSF-2, IFNB2, B-cell differentiation factor, CDF, HSF, IL-6 -
基因ID
- 3569
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途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
抗原
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