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USP5 抗体

USP5 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 1340CT704-170-140 unconjugated
产品编号 ABIN1944895
发货至: 中国
  • 抗原 See all USP5 抗体
    USP5 (Ubiquitin Specific Peptidase 5 (USP5))
    适用
    • 45
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 40
    • 7
    小鼠
    克隆类型
    • 41
    • 6
    单克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP5 antibody is un-conjugated
    应用范围
    • 35
    • 23
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5.
    克隆位点
    1340CT704-170-140
    亚型
    IgG1 kappa
    Top Product
    Discover our top product USP5 Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Falquet, Paquet, Frutiger, Hughes, Hoang-Van, Jaton: "cDNA cloning of a human 100 kDa de-ubiquitinating enzyme: the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2)." in: FEBS letters, Vol. 376, Issue 3, pp. 233-7, (1996) (PubMed).

  • 抗原
    USP5 (Ubiquitin Specific Peptidase 5 (USP5))
    别名
    USP5 (USP5 产品)
    别名
    ISOT antibody, AA407472 antibody, ISOT-1 antibody, Ucht antibody, ubiquitin specific peptidase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5, putative antibody, ubiquitin specific protease 5 antibody, ubiquitin specific peptidase 5 (isopeptidase T) antibody, USP5 antibody, CNH02890 antibody, EHI_049940 antibody, CC1G_12961 antibody, MCYG_01862 antibody, CGB_L3600C antibody, PY00546 antibody, Usp5 antibody
    背景
    Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
    分子量
    95786
    基因ID
    8078
    UniProt
    P45974
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