TAB1 抗体 (Center)
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- 抗原 See all TAB1 抗体
- TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
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抗原表位
- Center
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TAB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Synthetic peptide corresponding to 13 amino acids in the center of human TAB1.
- Top Product
- Discover our top product TAB1 Primary Antibody
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 3-100) antibody
TAB1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 205-504) antibodyTAB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) antibodyTAB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 205-504) antibodyTAB1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 601-712) antibodyTAB1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) antibodyTAB1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) antibodyTAB1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) antibodyTAB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (C-Term) antibodyTAB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) antibodyTAB1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
- 别名
- TAB1 (TAB1 产品)
- 别名
- 3'-Tab1 antibody, MAP3K7IP1 antibody, 2310012M03Rik antibody, Map3k7ip1 antibody, b2b449Clo antibody, TGF-beta activated kinase 1 (MAP3K7) binding protein 1 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 1 antibody, TAB1 antibody, Tab1 antibody
- 背景
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TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses.This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals.It has been shown that the C-terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF-beta, demonstrating how this protein can function as a mediator between TGF-beta receptors and TAK1.
- NCBI登录号
- NP_006107
- 途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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