TIGAR 抗体 (Center)
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- 抗原 See all TIGAR 抗体
- TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
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抗原表位
- Center
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIGAR antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 18 amino acid peptide from near the center of human TIGAR.
- Top Product
- Discover our top product TIGAR Primary Antibody
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anti-TP53 induced glycolysis regulatory phosphatase (TIGAR) (AA 24-188) antibody
TIGAR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TP53 induced glycolysis regulatory phosphatase (TIGAR) (AA 161-270) antibodyTIGAR 适用: 小鼠 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TP53 induced glycolysis regulatory phosphatase (TIGAR) (AA 1-270) antibodyTIGAR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TP53 induced glycolysis regulatory phosphatase (TIGAR) (AA 220-270) antibodyTIGAR 适用: 人 IHC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-TP53 induced glycolysis regulatory phosphatase (TIGAR) (Middle Region 1) antibodyTIGAR 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TP53 induced glycolysis regulatory phosphatase (TIGAR) (Middle Region 2) antibodyTIGAR 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TP53 induced glycolysis regulatory phosphatase (TIGAR) (Center) antibodyTIGAR 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
- 别名
- TIGAR (TIGAR 产品)
- 别名
- AA793651 antibody, AI595337 antibody, C79710 antibody, C85509 antibody, Tigar antibody, Trp53 induced glycolysis repulatory phosphatase antibody, Tigar antibody
- 背景
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The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers.Recent studies have demonstrated the ability of p53 to regulate the expression of several proteins involved in glycolysis and oxidative phosphorylation, such as TIGAR, SCO2, and phosphoglycerate mutase.TIGAR is a recently discovered protein that functions to regulate glycolysis and protect cells against oxidative stress.TIGAR is similar in structure to proteins in the phosphoglycerate mutase family, most notably 6-phosphofructo-2-kinase, suggesting TIGAR may function as a fructose bisphosphatase.Expression of TIGAR in transfected cells correlated with an inhibition of glycolysis and decreased levels of reactive oxygen species and p53-induced apoptosis, indicating that TIGAR may act to modulate the apoptotic response to p53, thereby allowing cells to survive mild or transient stresses.
Synonyms: Tp53-induced glycolysis and apoptosis regulator - NCBI登录号
- NP_065108
- 途径
- Warburg Effect
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