电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TIGAR 抗体 (Center)

TIGAR 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500907
发货至: 中国
  • 抗原 See all TIGAR 抗体
    TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
    抗原表位
    • 15
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 37
    • 33
    • 4
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 57
    • 1
    • 1
    克隆类型
    • 59
    多克隆
    标记
    • 24
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIGAR antibody is un-conjugated
    应用范围
    • 40
    • 26
    • 13
    • 13
    • 9
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects TIGAR at center.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    TIGAR antibody was raised against a 18 amino acid peptide from near the center of human TIGAR.
    亚型
    IgG
    Top Product
    Discover our top product TIGAR Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
    别名
    TIGAR (TIGAR 产品)
    别名
    AA793651 antibody, AI595337 antibody, C79710 antibody, C85509 antibody, Tigar antibody, Trp53 induced glycolysis repulatory phosphatase antibody, Tigar antibody
    背景
    The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. Recent studies have demonstrated the ability of p53 to regulate the expression of several proteins involved in glycolysis and oxidative phosphorylation, such as TIGAR, SCO2, and phosphoglycerate mutase. TIGAR is a recently discovered protein that functions to regulate glycolysis and protect cells against oxidative stress. TIGAR is similar in structure to proteins in the phosphoglycerate mutase family, most notably 6-phosphofructo-2-kinase, suggesting TIGAR may function as a fructose bisphosphatase. Expression of TIGAR in transfected cells correlated with an inhibition of glycolysis and decreased levels of reactive oxygen species and p53-induced apoptosis, indicating that TIGAR may act to modulate the apoptotic response to p53, thereby allowing cells to survive mild or transient stresses.Synonyms: 6-bisphosphatase TIGAR, C12orf5, Probable fructose-2, TP53-induced glycolysis and apoptosis regulator
    基因ID
    57103
    NCBI登录号
    NP_065108
    途径
    Warburg Effect
You are here:
客服