PAK4 抗体 (Center)
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- 抗原 See all PAK4 抗体
- PAK4 (P21-Activated Kinase 4 (PAK4))
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抗原表位
- Center
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAK4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 13 amino acid peptide from near the center of human PAK4.
- Top Product
- Discover our top product PAK4 Primary Antibody
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anti-P21-Activated Kinase 4 (PAK4) (AA 299-542) antibody
PAK4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 1-426) antibodyPAK4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 187-216) antibodyPAK4 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 187-216) antibodyPAK4 适用: 人, 小鼠 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 23-72) antibodyPAK4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼, Hamster, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 120-280) antibodyPAK4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 156-187) antibodyPAK4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 187-216) antibodyPAK4 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (pSer474) antibodyPAK4 适用: 人, 小鼠, 大鼠, Cow WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 68-157) antibodyPAK4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- PAK4 (P21-Activated Kinase 4 (PAK4))
- 别名
- PAK4 (PAK4 产品)
- 别名
- 5730488L07Rik antibody, AW555722 antibody, mKIAA1142 antibody, im:5916170 antibody, wu:fd12b01 antibody, zgc:92014 antibody, p21 (RAC1) activated kinase 4 antibody, p21 protein (Cdc42/Rac)-activated kinase 4 antibody, PAK4 antibody, Pak4 antibody, pak4 antibody
- 背景
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The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac.They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding.Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding.The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility.Much less is known about the second group, which includes PAK4, 5 and 6.These proteins are not activated by Cdc42/Rac binding.PAK4 was initially identified as a novel effector of Cdc42Hs.Co-expression of PAK4 and Cdc42Hs resulted in induction of filopodia and actin polymerization, showing that it is involved in cytoskeletal reorganization.Other experiments have shown PAK4 to be essential for embryonic viability and proper neuronal development.PAK4 has also been implicated in anchorage-independent growth of tumor cells and is required for activation of several cancer prosurvival pathways.
Synonyms: p21-activated kinase 4 - NCBI登录号
- NP_005875
- 途径
- RTK signaling
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