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PRDM16 抗体 (C-Term)

PRDM16 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887173
发货至: 中国
  • 抗原 See all PRDM16 抗体
    PRDM16 (PR Domain Containing 16 (PRDM16))
    抗原表位
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 17
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 15
    • 2
    • 1
    • 1
    克隆类型
    • 17
    • 2
    多克隆
    标记
    • 15
    • 2
    • 1
    • 1
    This PRDM16 antibody is un-conjugated
    应用范围
    • 13
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    17 amino acid peptide from near the carboxy terminus of human PRDM16.
    Top Product
    Discover our top product PRDM16 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    PRDM16 (PR Domain Containing 16 (PRDM16))
    别名
    PRDM16 (PRDM16 产品)
    别名
    PRDM16 antibody, wu:fc09g08 antibody, MEL1 antibody, PFM13 antibody, 5730557K01Rik antibody, C130091E20 antibody, csp1 antibody, mKIAA1675 antibody, mel1 antibody, PR/SET domain 16 antibody, PR domain containing 16 antibody, PRDM16 antibody, prdm16 antibody, Prdm16 antibody
    背景
    PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain.The reciprocal translocation t(1,3)(p36,q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36, q21)-positive MDS/AML.The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML.Recent studies have shown that PRDM16 normally acts as a Smad3 binding protein that may be important for the development of orofacial structures through modulation of the TGF-beta signaling pathway.Other experiments have indicated that PRDM16 controls a bidirectional cell fate switch between skeletal myoblasts and brown fat cells.
    Synonyms: PR domain containing 16, MEL1, PFM13
    途径
    Stem Cell Maintenance, Brown Fat Cell Differentiation
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