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DFFB 抗体 (AA 203-218)

DFFB 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1886855
发货至: 中国
  • 抗原 See all DFFB 抗体
    DFFB (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
    抗原表位
    • 15
    • 15
    • 14
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 203-218
    适用
    人, 小鼠, 大鼠
    宿主
    • 68
    • 4
    克隆类型
    • 69
    • 3
    多克隆
    标记
    • 30
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DFFB antibody is un-conjugated
    应用范围
    • 53
    • 28
    • 26
    • 26
    • 18
    • 14
    • 10
    • 7
    • 6
    • 4
    • 3
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Peptide corresponding to amino acids 203 to 218 of human DFF40.
    Top Product
    Discover our top product DFFB Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    DFFB (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
    别名
    DFF40 (DFFB 产品)
    别名
    CAD antibody, CPAN antibody, DFF-40 antibody, DFF2 antibody, DFF40 antibody, LOC100223514 antibody, 40kDa antibody, 5730477D02Rik antibody, Didff antibody, Cad antibody, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase antibody, DNA fragmentation factor subunit beta antibody, DNA fragmentation factor, beta polypeptide (caspase-activated DNase) antibody, DNA fragmentation factor, beta subunit antibody, CAD antibody, DFFB antibody, dffb antibody, LOC100223514 antibody, Dffb antibody
    背景
    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.These death signals finally cause the degradation of chromosomal DNA by activated DNase.A mouse DNase that causes DNA fragmentation was identified recently and designated CAD for caspase activated deoxyribonuclease.The human homologue of mouse CAD was more recently identified by three groups independently and termed CPAN, DFF40, and human CAD, respectively.DFF45/ICAD is the inhibitory protein of DFF40/CAD and forms complex with DFF40/CAD.Upon cleavage of DFF45/ICAD by activated caspase, DFF40/CAD is released and activated and eventually causes the degradation of DNA in the nuclei.Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death.
    Synonyms: CAD
    分子量
    40 kDa
    NCBI登录号
    NP_004393
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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