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DFFB 抗体 (AA 251-338)

DFFB 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872776
发货至: 中国
  • 抗原 See all DFFB 抗体
    DFFB (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
    抗原表位
    • 15
    • 14
    • 14
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-338
    适用
    • 56
    • 44
    • 24
    小鼠
    宿主
    • 72
    • 4
    克隆类型
    • 73
    • 3
    多克隆
    标记
    • 34
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DFFB antibody is un-conjugated
    应用范围
    • 58
    • 28
    • 25
    • 25
    • 18
    • 14
    • 10
    • 10
    • 5
    • 4
    • 3
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DFFB
    亚型
    IgG
    Top Product
    Discover our top product DFFB Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    DFFB (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
    别名
    DFFB (DFFB 产品)
    别名
    CAD antibody, CPAN antibody, DFF-40 antibody, DFF2 antibody, DFF40 antibody, LOC100223514 antibody, 40kDa antibody, 5730477D02Rik antibody, Didff antibody, Cad antibody, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase antibody, DNA fragmentation factor subunit beta antibody, DNA fragmentation factor, beta polypeptide (caspase-activated DNase) antibody, DNA fragmentation factor, beta subunit antibody, CAD antibody, DFFB antibody, dffb antibody, LOC100223514 antibody, Dffb antibody
    背景

    Synonyms: CAD, Caldesmon, Caspase activated deoxyribonuclease, Caspase activated DNase, Caspase activated nuclease, CDM, CPAN, Deoxyribonuclease III, caspase activated, DFF 40, DFF2, DFF40, Didff, DNA fragmentation factor 40 kDa subunit, DNA fragmentation factor subunit beta, DNA fragmentation factor, 40 Da, beta polypeptide caspase activated DNase, DNA fragmentation factor, 40 kD beta subunit, DNA fragmentation factor, 40 kD, beta polypeptide, DNA fragmentation factor, 40 kDa, beta polypeptide caspase activated DNase, DNA fragmentation factor, 40 kDa, beta polypeptide caspase-activated DNase, DNAation factor, beta subunit, DFFB_HUMAN.

    Background: Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of these variants has not been determined. [provided by RefSeq, Jul 2008].

    基因ID
    1677
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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