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UVRAG 抗体 (C-Term)

UVRAG 适用: 人 WB 宿主: 兔 Polyclonal RB13045 unconjugated
产品编号 ABIN1882151
发货至: 中国
  • 抗原 See all UVRAG 抗体
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    抗原表位
    • 9
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 540-569, C-Term
    适用
    • 58
    • 38
    • 30
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 4
    克隆类型
    • 56
    • 2
    多克隆
    标记
    • 26
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UVRAG antibody is un-conjugated
    应用范围
    • 51
    • 16
    • 13
    • 12
    • 12
    • 9
    • 9
    • 6
    • 5
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-569 amino acids from the C-terminal region of human UVRAG.
    克隆位点
    RB13045
    亚型
    Ig Fraction
    Top Product
    Discover our top product UVRAG Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Wei: "Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells." in: Neural regeneration research, Vol. 9, Issue 1, pp. 16-24, (2014) (PubMed).

    Bodemann, Orvedahl, Cheng, Ram, Ou, Formstecher, Maiti, Hazelett, Wauson, Balakireva, Camonis, Yeaman, Levine, White: "RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly." in: Cell, Vol. 144, Issue 2, pp. 253-67, (2011) (PubMed).

    Liang, Feng, Ku, Dotan, Canaani, Oh, Jung: "Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG." in: Nature cell biology, Vol. 8, Issue 7, pp. 688-99, (2006) (PubMed).

    Vogt, Affara, Davey, Hammer, Jobling, Lau, Mitchell, Schempp, Tyler-Smith, Williams, Yen, Rappold: "Report of the Third International Workshop on Y Chromosome Mapping 1997. Heidelberg, Germany, April 13-16, 1997." in: Cytogenetics and cell genetics, Vol. 79, Issue 1-2, pp. 1-20, (1998) (PubMed).

  • 抗原
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    别名
    UVRAG (UVRAG 产品)
    别名
    DHTX antibody, VPS38 antibody, p63 antibody, 9530039D02Rik antibody, AI648770 antibody, BB124205 antibody, Uvrag1 antibody, Uvragl antibody, zgc:56164 antibody, uvrag antibody, MGC81810 antibody, UVRAG antibody, MGC131135 antibody, CG6116 antibody, Dmel\\CG6116 antibody, UV radiation resistance associated antibody, UV radiation resistance associated gene antibody, UV radiation resistance associated S homeolog antibody, UV radiation resistance associated L homeolog antibody, UV-resistance associated gene antibody, UVRAG antibody, Uvrag antibody, uvrag antibody, uvrag.S antibody, uvrag.L antibody
    背景
    UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving the UVAG gene are associated with left-right axis malformation and mutations in the gene have been associated with colon cancer.
    分子量
    78151
    NCBI登录号
    NP_003360
    UniProt
    Q9P2Y5
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