UVRAG 产品
(UV Radiation Resistance Associated Gene (UVRAG))
Categories
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008].
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Featured UVRAG Categories
Recommended UVRAG 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (4)
Cat. No.
ABIN6150044
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (4)
Cat. No.
ABIN7175178
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN521294
Quantity
100 μg
Datasheet
Datasheet
Recommended UVRAG ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6201850
Quantity
96 tests
Datasheet
Datasheet
Recommended UVRAG 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324875
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324874
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3096275
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our UVRAG Products
: "NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex." in: Frontiers in cellular and infection microbiology, Vol. 8, pp. 403, (2019) (PubMed).: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." in: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).
: "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth." in: Nature communications, Vol. 6, pp. 7215, (2015) (PubMed).
: "Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells." in: Neural regeneration research, Vol. 9, Issue 1, pp. 16-24, (2014) (PubMed).
: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).
: "The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 185-91, (2011) (PubMed).
: "RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly." in: Cell, Vol. 144, Issue 2, pp. 253-67, (2011) (PubMed).
: "Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a ?-secretase-independent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 8, pp. 2781-91, (2011) (PubMed).
: "Rubicon controls endosome maturation as a Rab7 effector." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 45, pp. 19338-43, (2010) (PubMed).
: "Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1371-83, (2010) (PubMed).
Synonyms and alternative names related to UVRAG
UV radiation resistance associated (UVRAG), UV radiation resistance associated gene (Uvrag), UV radiation resistance associated gene (uvrag), UV radiation resistance associated (Uvrag), UV radiation resistance associated S homeolog (uvrag.S), UV radiation resistance associated L homeolog (uvrag.L), UV radiation resistance associated (uvrag), UV-resistance associated gene (Uvrag), 9530039D02Rik, AI648770, BB124205, CG6116, DHTX, Dmel\\CG6116, MGC81810, MGC131135, p63, uvrag, UVRAG, Uvrag1, Uvragl, VPS38, zgc:56164Protein level used designations for UVRAG
- UV radiation resistance-associated gene protein
- beclin 1 binding protein
- disrupted in heterotaxy
- UV radiation resistance associated
- UV radiation resistance associated gene
- UV radiation resistance-associated gene protein-like
- CG6116-PA
- CG6116-PB
- Uvrag-PA
- Uvrag-PB
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