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VAMP1/VAMP2 抗体 (full length)

The 绵羊 多克隆 anti-VAMP1/VAMP2 antibody (ABIN306588) specifically detects VAMP1/VAMP2 in IP 和 WB. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN306588
发货至: 中国
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Quick Overview for VAMP1/VAMP2 抗体 (full length) (ABIN306588)

抗原

VAMP1/VAMP2 (Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))

适用

人, 大鼠

宿主

绵羊

克隆类型

多克隆

应用范围

Immunoprecipitation (IP), Western Blotting (WB)
  • 抗原表位

    full length

    原理

    Sheep anti Human Vesicle Associated Membrane Protein (VAMP 1/2)

    交叉反应

    产品特性

    Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis. VAMP (also know as synaptobrevin) is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis. Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue. VAMP-1 and -2 are present in all tissues tested, including kidney, adrenal gland, liver, pancreas, thyroid, heart, and smooth muscle. The two isoforms are differentially expressed in various tissues and their level may depend on differentiation. VAMP-1 is restricted to exocrine pancreas and to kidney tubular cells, whereas VAMP-2 is the predominant isoform present in Langerhans islets and in glomerular cells. Both isoforms show a patchy vesicular intracellular distribution in confocal microscopy. Evidence for the importance of neuronal VAMPproteins in the physiology of all cells is indicated.

    纯化方法

    Ammonium Sulfate Precipitation

    免疫原

    Full length VAMP1/2 protein

    亚型

    IgG
  • 应用备注

    Applications: Western Blotting, Immunoprecipitation

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原

    VAMP1/VAMP2 (Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))

    别名

    Vesicle Associated Membrane Protein (VAMP 1/2)

    背景

    Sheep anti vesicle associated membrane protein 1 and 2, VAMP 1 and 2, VAMP1/2, VAMP 1/2, VAMP-1/2, Synaptobrevin 1 and 2
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