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UVRAG 抗体 (AA 375-425)

Name: UVRAG 抗体 (AA 375-425)
Brand: antibodies-online
SKU: ABIN7175178
Availability: OutOfStock

UVRAG 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated

Western blot All lanes: UVRAG antibody at 2 μg/mL Lane 1: SH-SY5Y whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 79, 36 kDa Observed band size: 79 kDa (UVRAG 抗体 (AA 375-425))

Immunohistochemistry of paraffin-embedded human lung cancer using ABIN7175178 at dilution of 1:100 (UVRAG 抗体 (AA 375-425))

IHC

Immunohistochemistry of paraffin-embedded human liver cancer using ABIN7175178 at dilution of 1:100 (UVRAG 抗体 (AA 375-425))

IHC

Immunofluorescent analysis of HepG2 cells using ABIN7175178 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) (UVRAG 抗体 (AA 375-425))

4 images

产品编号 ABIN7175178

发货至: 中国

Datasheet as PDF

抗原 See all UVRAG 抗体

UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
抗原表位
9

9

5

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 375-425
适用
57

38

30

1

1

1

1

1

1

1

1
人
宿主
53

4
兔
Compatible Secondaries
克隆类型
55

2
多克隆
标记
25

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This UVRAG antibody is un-conjugated
应用范围
50

15

13

12

11

9

8

6

5

2

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

交叉反应

人

纯化方法

>95%, Protein G purified

免疫原

Recombinant Human UV radiation resistance-associated gene protein (375-425AA)

亚型

IgG

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anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (FITC)
UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC

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UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE

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UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP

anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (Atto 488)
UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 488

anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (Atto 594)
UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 594

anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 666-699), (C-Term) antibody
UVRAG 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB10849 unconjugated

anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 375-425) antibody
UVRAG 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

限制

仅限研究用
状态

Liquid

缓冲液

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

别名

UVRAG (UVRAG 产品)

别名

DHTX antibody, VPS38 antibody, p63 antibody, 9530039D02Rik antibody, AI648770 antibody, BB124205 antibody, Uvrag1 antibody, Uvragl antibody, zgc:56164 antibody, uvrag antibody, MGC81810 antibody, UVRAG antibody, MGC131135 antibody, CG6116 antibody, Dmel\\CG6116 antibody, UV radiation resistance associated antibody, UV radiation resistance associated gene antibody, UV radiation resistance associated S homeolog antibody, UV radiation resistance associated L homeolog antibody, UV-resistance associated gene antibody, UVRAG antibody, Uvrag antibody, uvrag antibody, uvrag.S antibody, uvrag.L antibody

背景

Background: Versatile protein that is involved in regulation of differenent cellular pathways implicated in membrane trafficking. Involved in regulation of the COPI-dependent retrograde transport from Golgi and the endoplasmic reticulum by associating with the NRZ complex, the function is dependent on its binding to phosphatidylinositol 3-phosphate (PtdIns(3)P) (PubMed:24056303). During autophagy acts as regulatory subunit of the alternative PI3K complex II (PI3KC3-C2) that mediates formation of phosphatidylinositol 3-phosphate and is believed to be involved in maturation of autophagosomes and endocytosis. Activates lipid kinase activity of PIK3C3. Involved in the regulation of degradative endocytic trafficking and cytokinesis, and in regulation of ATG9A transport from the Golgi to the autophagosome, the functions seems to implicate its association with PI3KC3-C2 (PubMed:16799551, PubMed:20643123, PubMed:24056303). Involved in maturation of autophagosomes and degradative endocytic trafficking independently of BECN1 but depending on its association with a class C Vps complex (possibly the HOPS complex), the association is also proposed to promote autophagosome recruitment and activation of Rab7 and endosome-endosome fusion events (PubMed:18552835). Enhances class C Vps complex (possibly HOPS complex) association with a SNARE complex and promotes fusogenic SNARE complex formation during late endocytic membrane fusion (PubMed:24550300). In case of negative-strand RNA virus infection is required for efficient virus entry, promotes endocytic transport of virions and is implicated in a VAMP8-specific fusogenic SNARE complex assembly (PubMed:24550300).
Aliases: Beclin 1 binding protein antibody, DHTX antibody, Disrupted in heterotaxy antibody, p63 antibody, UV radiation resistance associated antibody, UV radiation resistance associated gene antibody, UV radiation resistance associated gene protein antibody, UV radiation resistance-associated gene protein antibody, UVRAG antibody, UVRAG_HUMAN antibody, VPS38 antibody

UniProt

Q9P2Y5