(2 references)-
- 抗原 See all FBXW4 抗体
- FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
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抗原表位
- AA 341-370, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXW4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This FBXW4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human FBXW4.
- 克隆位点
- RB42400
- 亚型
- Ig Fraction
- Top Product
- Discover our top product FBXW4 Primary Antibody
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anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 143-412) antibody
FBXW4 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 41-140) antibodyFBXW4 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) antibodyFBXW4 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 5-186) antibodyFBXW4 适用: 人, 大鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 1-412) antibodyFBXW4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 334-383) antibodyFBXW4 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 豚鼠, 猴, 犬, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (C-Term) antibodyFBXW4 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 豚鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Frequency of genomic rearrangements involving the SHFM3 locus at chromosome 10q24 in syndromic and non-syndromic split-hand/foot malformation." in: American journal of medical genetics. Part A, Vol. 140, Issue 13, pp. 1375-83, (2006) (PubMed).
: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).
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: "Frequency of genomic rearrangements involving the SHFM3 locus at chromosome 10q24 in syndromic and non-syndromic split-hand/foot malformation." in: American journal of medical genetics. Part A, Vol. 140, Issue 13, pp. 1375-83, (2006) (PubMed).
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- 抗原
- FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
- 别名
- FBXW4 (FBXW4 产品)
- 别名
- dac antibody, hag antibody, hagoromo antibody, wu:fk63g06 antibody, FBXW4 antibody, DAC antibody, FBW4 antibody, FBWD4 antibody, SHFM3 antibody, SHSF3 antibody, Dac antibody, Fbw4 antibody, dactylin antibody, dactylyn antibody, F-box and WD repeat domain containing 4 antibody, F-box and WD-40 domain protein 4 antibody, fbxw4 antibody, FBXW4 antibody, Fbxw4 antibody
- 背景
- This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds, disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22.
- 分子量
- 46337
- NCBI登录号
- NP_071322
- UniProt
- P57775
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