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FBXW4 抗体

FBXW4 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7264203
发货至: 中国
  • 抗原 See all FBXW4 抗体
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    适用
    • 33
    • 12
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    小鼠
    宿主
    • 34
    • 2
    克隆类型
    • 36
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 3
    • 3
    This FBXW4 antibody is un-conjugated
    应用范围
    • 29
    • 27
    • 9
    • 4
    • 3
    • 3
    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human FBXW4 (NP_071322.1).
    亚型
    IgG
    Top Product
    Discover our top product FBXW4 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    别名
    FBXW4 (FBXW4 产品)
    别名
    dac antibody, hag antibody, hagoromo antibody, wu:fk63g06 antibody, FBXW4 antibody, DAC antibody, FBW4 antibody, FBWD4 antibody, SHFM3 antibody, SHSF3 antibody, Dac antibody, Fbw4 antibody, dactylin antibody, dactylyn antibody, F-box and WD repeat domain containing 4 antibody, F-box and WD-40 domain protein 4 antibody, fbxw4 antibody, FBXW4 antibody, Fbxw4 antibody
    背景
    This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds, disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22.
    分子量

    Observed_MW: 46 kDa

    Calculated_MW: 46 kDa

    基因ID
    6468
    UniProt
    P57775
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