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CSF2RA 抗体 (C-Term)

CSF2RA 适用: 人 WB 宿主: 兔 Polyclonal RB40748 unconjugated
产品编号 ABIN1881231
发货至: 中国
  • 抗原 See all CSF2RA 抗体
    CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
    抗原表位
    • 13
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 366-394, C-Term
    适用
    • 47
    • 11
    • 3
    宿主
    • 44
    • 8
    克隆类型
    • 45
    • 7
    多克隆
    标记
    • 26
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSF2RA antibody is un-conjugated
    应用范围
    • 35
    • 23
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This CSF2RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-394 amino acids from the C-terminal region of human CSF2RA.
    克隆位点
    RB40748
    亚型
    Ig Fraction
    Top Product
    Discover our top product CSF2RA Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Mirza, Walker, Chen, Murphy, Young: "The Ig-like domain of human GM-CSF receptor alpha plays a critical role in cytokine binding and receptor activation." in: The Biochemical journal, Vol. 426, Issue 3, pp. 307-17, (2010) (PubMed).

    Martinez-Moczygemba, Doan, Elidemir, Fan, Cheung, Lei, Moore, Tavana, Lewis, Zhu, Muzny, Gibbs, Huston: "Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1." in: The Journal of experimental medicine, Vol. 205, Issue 12, pp. 2711-6, (2008) (PubMed).

    Hansen, Hercus, McClure, Stomski, Dottore, Powell, Ramshaw, Woodcock, Xu, Guthridge, McKinstry, Lopez, Parker: "The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation." in: Cell, Vol. 134, Issue 3, pp. 496-507, (2008) (PubMed).

  • 抗原
    CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
    别名
    CSF2RA (CSF2RA 产品)
    别名
    CD116 antibody, CDw116 antibody, CSF2R antibody, CSF2RAX antibody, CSF2RAY antibody, CSF2RX antibody, CSF2RY antibody, GM-CSF-R-alpha antibody, GMCSFR antibody, GMR antibody, SMDP4 antibody, Csfgmra antibody, GM-CSF-Ra antibody, GM-CSFR antibody, colony stimulating factor 2 receptor, alpha antibody, colony stimulating factor 2 receptor alpha subunit antibody, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) antibody, CSF2RA antibody, Csf2ra antibody
    背景
    The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
    分子量
    46207
    NCBI登录号
    NP_001155001, NP_001155002, NP_001155003, NP_001155004, NP_006131, NP_758448, NP_758449, NP_758450, NP_758452
    UniProt
    P15509
    途径
    JAK/STAT Signaling
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