(3 references)-
- 抗原 See all CSF2RA 抗体
- CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CSF2RA antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody 4H1 recognizes an extracellular epitope of human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- CD116-transfected COS cells
- 克隆位点
- 4H1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CSF2RA Primary Antibody
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anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) (AA 1-400) antibody
CSF2RA 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G5 unconjugated
anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) (Center) antibodyCSF2RA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) (AA 101-230) antibodyCSF2RA 适用: 人, 小鼠 IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) (AA 23-320) antibodyCSF2RA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) antibodyCSF2RA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) (AA 1-400) antibodyCSF2RA 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) antibodyCSF2RA 适用: 人 WB, IP, FACS, IHC (fro), CyTOF 宿主: 小鼠 Monoclonal 4H1 unconjugated
anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) (AA 23-150) antibodyCSF2RA 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) (AA 204-360) antibodyCSF2RA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) (AA 23-320) antibodyCSF2RA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Peripheral monocyte functions and activation in patients with quiescent Crohn's disease." in: PLoS ONE, Vol. 8, Issue 4, pp. e62761, (2013) (PubMed).
: "Therapeutic effect of human iPS-cell-derived myeloid cells expressing IFN-? against peritoneally disseminated cancer in xenograft models." in: PLoS ONE, Vol. 8, Issue 6, pp. e67567, (2013) (PubMed).
: "IL-15 trans-presentation promotes human NK cell development and differentiation in vivo." in: The Journal of experimental medicine, Vol. 206, Issue 1, pp. 25-34, (2009) (PubMed).
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: "Peripheral monocyte functions and activation in patients with quiescent Crohn's disease." in: PLoS ONE, Vol. 8, Issue 4, pp. e62761, (2013) (PubMed).
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- 抗原
- CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
- 别名
- CD116 (CSF2RA 产品)
- 别名
- CD116 antibody, CDw116 antibody, CSF2R antibody, CSF2RAX antibody, CSF2RAY antibody, CSF2RX antibody, CSF2RY antibody, GM-CSF-R-alpha antibody, GMCSFR antibody, GMR antibody, SMDP4 antibody, Csfgmra antibody, GM-CSF-Ra antibody, GM-CSFR antibody, colony stimulating factor 2 receptor, alpha antibody, colony stimulating factor 2 receptor alpha subunit antibody, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) antibody, CSF2RA antibody, Csf2ra antibody
- 背景
- Colony stimulating factor 2 receptor alpha subunit,CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5- receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.,CSF2RA, GMR, CSF2R, SMDP4, GMCSFR
- 基因ID
- 1438
- UniProt
- P15509
- 途径
- JAK/STAT Signaling
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