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MUC1 抗体

MUC1 适用: 人 IHC, ELISA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal VU-11D1 unconjugated
产品编号 ABIN1837986
发货至: 中国
  • 抗原 See all MUC1 抗体
    MUC1 (Mucin 1 (MUC1))
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    小鼠
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    This MUC1 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    VU-11D1 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of mAb VU11D1 is the 7-mer TSAPDTR of the MUC1 tandem repeat as established with epitope fingerprinting.
    纯化方法
    Purified
    免疫原
    Live cells (107 cells/dose in PBS) of human breast cancer cell line ZR-75-1. Splenocytes were fused with SP2/0 mouse myeloma cells. Stability of the hybridomas was established by subcloning four times.
    克隆位点
    VU-11D1
    亚型
    IgG1
    Top Product
    Discover our top product MUC1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 4°C.
  • 抗原
    MUC1 (Mucin 1 (MUC1))
    别名
    EMA / MUC1 (MUC1 产品)
    别名
    CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
    背景
    Name/Gene ID: MUC1
    Family: Mucin

    Synonyms: MUC1, CA15-3, CD227, Carcinoma-associated mucin, CD227 antigen, DF3 antigen, Episialin, Epithelial membrane antigen, H23 antigen, H23AG, Krebs von den Lungen-6, MAM6, MUC1/ZD, MUC-1/SEC, Mucin-1, Pem, KL-6, MUC-1/X, Tumor-associated mucin, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, PUM, EMA, MUC-1, Mucin 1, transmembrane
    基因ID
    4582
    UniProt
    P15941
    途径
    Negative Regulation of intrinsic apoptotic Signaling
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