This antibody recognises the MUC2 mucin, and shows no cross-reactivity with MUC1, MUC3 or MUC4 mucins. In tissue sections SM1709 recognises colon, liver and prostate tissues strongly. The antibody recognises malignant colonic mucosa as well as normal mucosa.
纯化方法
Affinity Chromatography on Protein G
免疫原
MUC2 tandem repeat peptide. Spleen cells from immunised Balb/c mice were fused with cells of a mouse NSO myeloma cell line.
Western Blot. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections. Recommended Positive Control: Normal colon Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
MUC2 expression is detected in such human tissues as normal colon, breast, prostate, salivary gland and in gastrointestinal, colonic, breast and prostate neoplasia. This antibody labels MUC2 in normal colon and colonic carcinomas where it produces intense perinuclear staining in goblet cells. It also reacts with normal and neoplastic breast tissues and with prostate adenocarcinoma.Synonyms: Intestinal mucin-2, MUC-2, MUC2, SMUC