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MUC2 产品

(Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008].

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Featured MUC2 Categories

MUC2 抗体

High quality antibodies with extensive validation data.

MUC2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MUC2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MUC2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB, IF, IHC (p), ICC, IHC (fro), FISH
Validations
  • (1)
  • (10)
Cat. No. ABIN2854828
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (6)
Cat. No. ABIN7429040
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IF
Validations
  • (7)
Cat. No. ABIN7268690
Quantity 100 μL
Datasheet Datasheet

Recommended MUC2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (5)
Cat. No. ABIN6730976
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6957899
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957900
Quantity 96 tests
Datasheet Datasheet

Recommended MUC2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391753
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391756
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401416
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MUC2 Products

Park, Kang, Paek, Georgescu, Chang, Yi, Wilkins, Karakasheva, Hamilton, Huh: "Geometric engineering of organoid culture for enhanced organogenesis in a dish." in: Nature methods, Vol. 19, Issue 11, pp. 1449-1460, (2022) (PubMed).

Zhang, Tai, Tang, Zhao, Tong, Gao, Tang: "Compromised Ileal Mucus Barrier Due to Impaired Epithelial Homeostasis Caused by Notch1 Signaling in Cirrhotic Rats." in: Digestive diseases and sciences, Vol. 66, Issue 1, pp. 131-142, (2021) (PubMed).

Han, Lei, Yang, Shen, Zheng, Jin, Cao, Yao: "A Metagenomic Insight Into the Hindgut Microbiota and Their Metabolites for Dairy Goats Fed Different Rumen Degradable Starch." in: Frontiers in microbiology, Vol. 12, pp. 651631, (2021) (PubMed).

Miyake, Lee, Chusilp, Bhalla, Li, Pitino, Seo, OConnor, Pierro: "Human breast milk exosomes attenuate intestinal damage." in: Pediatric surgery international, Vol. 36, Issue 2, pp. 155-163, (2020) (PubMed).

Stine, Sakers, TeSlaa, Kissig, Stine, Kwon, Cheng, Lim, Kaestner, Rabinowitz, Seale: "PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism." in: Cell stem cell, Vol. 25, Issue 6, pp. 830-845.e8, (2020) (PubMed).

Liu, Saitz-Rojas, Smith, Gonyar, In, Kovbasnjuk, Zachos, Donowitz, Nataro, Ruiz-Perez: "Mucus layer modeling of human colonoids during infection with enteroaggragative E. coli." in: Scientific reports, Vol. 10, Issue 1, pp. 10533, (2020) (PubMed).

Ma, Yeom, Lim: "Exogenous NAD+ Stimulates MUC2 Expression in LS 174T Goblet Cells via the PLC-Delta/PTGES/PKC-Delta/ERK/CREB Signaling Pathway." in: Biomolecules, Vol. 10, Issue 4, (2020) (PubMed).

Janardhan, Jensen, Clayton, Herbert: "Immunohistochemistry in Investigative and Toxicologic Pathology." in: Toxicologic pathology, Vol. 46, Issue 5, pp. 488-510, (2019) (PubMed).

Li, Hock, Wu, Minich, Botts, Lee, Antounians, Miyake, Koike, Chen, Zani, Sherman, Pierro: "Bovine milk-derived exosomes enhance goblet cell activity and prevent the development of experimental necrotizing enterocolitis." in: PLoS ONE, Vol. 14, Issue 1, pp. e0211431, (2019) (PubMed).

Li, Lee, Filler, Hock, Wu, Li, Chen, Koike, Ip, Chi, Zani-Ruttenstock, Määttänen, Gonska, Delgado-Olguin, Zani, Sherman, Pierro: "Inhibition of corticotropin-releasing hormone receptor 1 and activation of receptor 2 protect against colonic injury and promote epithelium repair." in: Scientific reports, Vol. 7, pp. 46616, (2019) (PubMed).

Synonyms and alternative names related to MUC2

mucin 2 (Muc2), mucin 2, oligomeric mucus/gel-forming (MUC2), mucin-2 (LOC100724045), mucin 2, oligomeric mucus/gel-forming (Muc2), 2010015E03Rik, HH-Muc, MCM, MLP, MUC-2, SMUC, wnn

Protein level used designations for MUC2

  • colonic mucin
  • mucin-2
  • secreted gel-forming mucin
  • intestinal mucin-2
  • mucin 2, intestinal/tracheal
  • mucin-like protein
  • MUC-2
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