TNFRSF1A 抗体
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- 抗原 See all TNFRSF1A 抗体
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 纯化方法
- Affinity chromatograophy
- 免疫原
- Highly pure (> 98 %) recombinant human sTNF-Receptor I
- Top Product
- Discover our top product TNFRSF1A Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 248-428) antibody
TNFRSF1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 22-211) antibodyTNFRSF1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibodyTNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (HRP)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (FITC)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (Alkaline Phosphatase (AP))TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (Biotin)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (PE)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (APC)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 20-43) antibody (PerCP)TNFRSF1A 适用: 小鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal PerCP
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- 应用备注
- ELISA: Direct: To detect hsTNF-Receptor I (using 100 μL/well antibody solution) aconcentration of 0.25 - 1.0 μg/mL of this antibody is required. In conjunction withcompatible secondary reagents, it allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hsTNF-Receptor I. Sandwich: To detect hsTNF-Receptor I (using 100 μL/well antibody solution) aconcentration of 0.25 - 1.0 μg/mL of this antibody is required. This In conjunction with
- 限制
- 仅限研究用
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- 溶解方式
- Centrifuge vial prior to opening. Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1 - 1.0 mg/mL.
- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- 抗原
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
- 别名
- CD120a / TNFR1 (TNFRSF1A 产品)
- 别名
- CD120a antibody, FPF antibody, MS5 antibody, TBP1 antibody, TNF-R antibody, TNF-R-I antibody, TNF-R55 antibody, TNFAR antibody, TNFR1 antibody, TNFR1-d2 antibody, TNFR55 antibody, TNFR60 antibody, p55 antibody, p55-R antibody, p60 antibody, TNF-R1 antibody, TNF-alphaR1 antibody, TNFRI antibody, TNFRp55 antibody, TNFalpha-R1 antibody, Tnfr-2 antibody, Tnfr1 antibody, fpf antibody, tbp1 antibody, p55-r antibody, tnf-r antibody, tnfar antibody, tnfr1 antibody, cd120a antibody, tnfr55 antibody, tnfr60 antibody, xtnfr1 antibody, wu:fj65b10 antibody, zgc:85914 antibody, TNFR I antibody, TNFRSF1A antibody, TNFA antibody, cTNF antibody, TNF receptor superfamily member 1A antibody, tumor necrosis factor receptor superfamily, member 1a antibody, TNF receptor superfamily member 1A S homeolog antibody, tumor necrosis factor antibody, TNFRSF1A antibody, Tnfrsf1a antibody, tnfrsf1a.S antibody, tnfrsf1a antibody, TNF antibody
- 背景
- Tumor Necrosis Factor (TNF) is a cytokine whose function is mediated through two distinct cell surface receptors (TNF Receptor I and TNF Receptor II) that are included in the TNF Receptor superfamily along with FAS antigen and CD40. TNF Receptors I and II are 55 and 75 kDa members, respectively, of a family of cell surface molecules including nerve growth factor receptor, Fas/Apo1, CD30, OX40, and 41BB, which are characterized by cysteine rich motifs in the extracellular domain. While TNF Receptor I and TNF Receptor II share 28 % sequence homology in the extracellular domains, their intracellular domains lack sequence homology, suggesting that they differ in their internal signal transduction pathways. TNF Receptor I contains an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein), and subsequent interactions with FADD. TNF Receptor I can also activate the transcription factor NFkB via TRAF2 (TNF Receptor associated factor 2). The cytoplasmic domain of TNF Receptor I can directly interact with Jak kinase, thereby activating the JAK/STAT signal transduction cascade. TNF Receptor I is expressed by virtually all nucleated mammalian cells, including hepatocytes, monocytes and neutrophils, cardiac muscle cells, endothelial cells, and CD34 + hematopoietic progenitors. Both TNF alpha and TNF beta bind to TNF Receptor I.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
- 基因ID
- 9606
- UniProt
- P19438
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway
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