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Integrin beta 2 抗体 (PE)

ITGB2 适用: Pig FACS 宿主: 小鼠 Monoclonal PNK-I PE
产品编号 ABIN180773
发货至: 中国
  • 抗原 See all Integrin beta 2 (ITGB2) 抗体
    Integrin beta 2 (ITGB2)
    适用
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    Pig
    宿主
    • 99
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Integrin beta 2 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises the Porcine homologue of Human CD18. Clone PNK-I immunoprecipitates molecules of 166, 155 and 95 kDa under reducing and non-reducing conditions. Clone PNK-I has been reported to inhibit Porcine NK activity without affecting antibody-dependent cellular cytoxicity.
    产品特性
    Synonyms: Integrin beta-2, MFI7, Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunitbeta, Complement receptor C3 subunit beta
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Porcine large granular lymphocytes. Spleen cells from immunised Balb/c mice were fusedwith cells of the mouse P3-X63-Ag8. 653 myeloma cell line.
    克隆位点
    PNK-I
    亚型
    IgG1
    Top Product
    Discover our top product ITGB2 Primary Antibody
  • 应用备注
    Flow Cytometry: use 10 μL of neat antibody to label 10^6 cells in 10 l.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1.0 mL distilled water.
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % BSA and 5 % Sucrose
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at +4 °C. This product should be stored undiluted. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    Integrin beta 2 (ITGB2)
    别名
    CD18 / ITGB2 (ITGB2 产品)
    别名
    CD18 antibody, LAD antibody, LCAMB antibody, LFA-1 antibody, MAC-1 antibody, MF17 antibody, MFI7 antibody, 2E6 antibody, AI528527 antibody, Cd18 antibody, Lfa1 antibody, ITGB2 antibody, itgb2 antibody, itgb2-a antibody, itgb2-b antibody, integrin subunit beta 2 antibody, integrin beta 2 antibody, integrin subunit beta 2 S homeolog antibody, ITGB2 antibody, Itgb2 antibody, itgb2.S antibody
    背景
    CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
    基因ID
    396943
    UniProt
    P53714
    途径
    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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