电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PINK1 抗体 (AA 258-274)

PINK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1738112
发货至: 中国
  • 抗原 See all PINK1 抗体
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    抗原表位
    • 20
    • 12
    • 12
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 258-274
    适用
    • 90
    • 50
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 72
    • 32
    • 1
    克隆类型
    • 76
    • 31
    多克隆
    标记
    • 50
    • 10
    • 9
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PINK1 antibody is un-conjugated
    应用范围
    • 83
    • 53
    • 47
    • 17
    • 15
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Reacts with human PINK1.
    纯化方法
    Purified
    免疫原
    Synthetic peptide corresponding to amino acids 258-274 (YRKSKRGPKQLAPHPNI) of human PINK1 conjugated to KLH.
    亚型
    IgG
    Top Product
    Discover our top product PINK1 Primary Antibody
  • 应用备注
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    WB 1:500 dilution

    Positive control: Transfected cell lines
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.4,
    注意事项
    Dilute in PBS or medium which is identical to that used in the assay system.
    储存条件
    4 °C/-20 °C
    储存方法
    Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
    有效期
    6 months
  • 抗原
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    别名
    PINK1 (PINK1 产品)
    别名
    BEST:GH23468 antibody, CG4523 antibody, Dmel\\CG4523 antibody, PINK antibody, PINK1 antibody, dPINK1 antibody, dPink1 antibody, pink1 antibody, wu:fc39e12 antibody, zgc:101729 antibody, BRPK antibody, PARK6 antibody, 1190006F07Rik antibody, AU042772 antibody, AW557854 antibody, mFLJ00387 antibody, PTEN-induced putative kinase 1 antibody, PTEN induced putative kinase 1 antibody, Pink1 antibody, PINK1 antibody, pink1 antibody
    背景
    PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers.It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease. It protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.

    Serine/threonine-protein kinase PINK1, mitochondrial BRPK PTEN-induced putative kinase protein 1 Gene name: PINK1
    基因ID
    65018
    UniProt
    Q9BXM7
    途径
    Autophagy
You are here:
客服