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CHEK1 抗体

This anti-CHEK1 antibody is a 兔 单克隆 antibody detecting CHEK1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN1680915
发货至: 中国

Quick Overview for CHEK1 抗体 (ABIN1680915)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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宿主

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克隆类型

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单克隆

标记

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This CHEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 交叉反应

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Chk1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    CHEK1

    背景

    The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011],CHK1,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Cycle,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G1/S Checkpoint,G2/M DNA Damage Checkpoint,Kinase,Kinase_Serine/threonine kinases,Protein phosphorylation,Signal Transduction,CHEK1

    分子量

    54 kDa

    基因ID

    1111

    UniProt

    O14757

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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