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HSP27 抗体

HSPB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A5 unconjugated
产品编号 ABIN165408
发货至: 中国
  • 抗原 See all HSP27 (HSPB1) 抗体
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This HSP27 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
    免疫原
    Recombinant Hsp27, Accession / GI number: NP_001531
    克隆位点
    2A5
    亚型
    Kappa
    Top Product
    Discover our top product HSPB1 Primary Antibody
  • 应用备注
    Recommended dilution 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1mg/ml
    缓冲液
    In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    别名
    Hsp27 (HSPB1 产品)
    别名
    CMT2F antibody, HMN2B antibody, HS.76067 antibody, HSP27 antibody, HSP28 antibody, Hsp25 antibody, SRP27 antibody, 27kDa antibody, Hsp27 antibody, cb153 antibody, cb660 antibody, hsp1 antibody, hsp25 antibody, hsp27 antibody, id:ibd2821 antibody, sb:cb660 antibody, zgc:103437 antibody, HSPB1 antibody, cmt2f antibody, hs.76067 antibody, hsp28 antibody, heat shock protein family B (small) member 1 antibody, heat shock protein 1 antibody, heat shock protein, alpha-crystallin-related, 1 antibody, heat shock protein family B (small) member 1 L homeolog antibody, HSPB1 antibody, Hspb1 antibody, hspb1 antibody, hspb1.L antibody
    背景
    Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38). Hsp27 forms a multimeric complex within cells, and its primary chaperone function, like other small Hsps, appears to be the stabilization of denatured or aggregated proteins in a refolding competent state.
    途径
    MAPK Pathway, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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