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CD3 epsilon 抗体

CD3E 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal 145-2C11 unconjugated
产品编号 ABIN161365
发货至: 中国
  • 抗原 See all CD3 epsilon (CD3E) 抗体
    CD3 epsilon (CD3E)
    适用
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    小鼠
    宿主
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    仓鼠
    克隆类型
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    单克隆
    标记
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    This CD3 epsilon antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse CD3
    纯化方法
    Purified
    免疫原
    H-2Kb sp . Fusion Partner: Murine myeloma cell line SP2/0 . Donor: BALB/c
    克隆位点
    145-2C11
    亚型
    IgG
    Top Product
    Discover our top product CD3E Primary Antibody
  • 限制
    仅限研究用
  • 浓度
    0.5 µg/10 cells
    储存条件
    4 °C
  • 抗原
    CD3 epsilon (CD3E)
    别名
    CD3e (CD3E 产品)
    别名
    cd3e antibody, CD3E antibody, t3e antibody, tcre antibody, AI504783 antibody, CD3 antibody, CD3epsilon antibody, T3e antibody, T3E antibody, TCRE antibody, CD3e molecule antibody, CD3 antigen, epsilon polypeptide antibody, cd3e antibody, CD3E antibody, Cd3e antibody
    背景
    Anti-mouse CD3 monoclonal antibody is specific for a 25 kDa protein component ( -T3) of the antigen specific T cell receptor on all mouse strains tested. The -T3 protein has been shown to be non-covalently associated on the cell surface heterodimer of the CD3 associated complex. This monoclonal antibody reacts with all mature T cells and can both activate and inhibit T cell function (1). This fact identifies -T3 as a cell surface protein involved in the transduction of activation signals. All peripheral T cells express this determinant however B cells and bone marrow cells have proven to be negative. Although the expression of this particular epitope on peripheral T cells is uniformly high, staining of thymocytes reveals distinct subpopulations of cells differing in the level of expression of this marker. This antibody will prove useful in studying the role of various components of the TCR complex in T cell activation and development, and will allow for the development of an animal model in which to investigate the immunoregulatory effects of in vivo administration of anti-CD3 antibodies, an area of obvious clinical
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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