CD3 epsilon 抗体 (AA 23-207)
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Quick Overview for CD3 epsilon 抗体 (AA 23-207) (ABIN3043805)
抗原
See all CD3 epsilon (CD3E) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-207
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原理
- Anti-CD3 epsilon/CD3E Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human CD3 epsilon shares 65% amino acid (aa) sequence identity with mouse CD3 epsilon.
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产品特性
- Anti-CD3 epsilon/CD3E Antibody. Tested in IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Chicken, Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD3 epsilon recombinant protein (Position: D23-I207). Human CD3 epsilon shares 65% amino acid (aa) sequence identity with mouse CD3 epsilon.
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat, Chicken Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Mouse, Rat Immunocytochemistry , 0.5-1 μg/mL, Human Immunofluorescence, 2 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "The pathological features of ectopic lymphoid neogenesis in idiopathic dacryoadenitis." in: BMC ophthalmology, Vol. 16, pp. 66, (2017) (PubMed).
: "Effectiveness of immune therapy combined with chemotherapy on the immune function and recurrence rate of cervical cancer." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 1063-1067, (2015) (PubMed).
: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).
: "Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients." in: Journal of translational medicine, Vol. 8, pp. 47, (2010) (PubMed).
: "Morphological observation of tumor infiltrating immunocytes in human rectal cancer." in: World journal of gastroenterology, Vol. 12, Issue 11, pp. 1757-60, (2006) (PubMed).
: "Effect of Hejie decoction on T cell immune state of chronic hepatitis B patients." in: World journal of gastroenterology, Vol. 10, Issue 10, pp. 1436-9, (2005) (PubMed).
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- CD3 epsilon (CD3E)
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别名
- CD3E
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背景
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Background: CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11. It is mapped to 11q23.3. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.
Gene Full Name: CD3 epsilon subunit of T-cell receptor complex
Sequence Similarities: Contains 1 Ig-like (immunoglobulin-like) domain.
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分子量
- 23 kDa
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基因ID
- 916
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UniProt
- P07766
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途径
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
抗原
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