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NR1H4 抗体 (N-Term)

NR1H4 适用: 人 WB 宿主: 兔 Polyclonal RB39466 unconjugated
产品编号 ABIN1539134
发货至: 中国
  • 抗原 See all NR1H4 抗体
    NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
    抗原表位
    • 16
    • 11
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-46, N-Term
    适用
    • 55
    • 28
    • 27
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    宿主
    • 52
    • 5
    • 1
    克隆类型
    • 53
    • 5
    多克隆
    标记
    • 28
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NR1H4 antibody is un-conjugated
    应用范围
    • 50
    • 27
    • 13
    • 13
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    预测反应
    B
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This NR1H4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human NR1H4.
    克隆位点
    RB39466
    亚型
    Ig Fraction
    Top Product
    Discover our top product NR1H4 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    NR1H4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
    别名
    NR1H4 (NR1H4 产品)
    别名
    zgc:110190 antibody, zgc:92742 antibody, NR1H4 antibody, BAR antibody, FXR antibody, HRR-1 antibody, HRR1 antibody, RIP14 antibody, AI957360 antibody, Fxr antibody, Rxrip14 antibody, nuclear receptor subfamily 1, group H, member 5 S homeolog antibody, nuclear receptor subfamily 1, group H, member 4 antibody, nuclear receptor subfamily 1 group H member 4 antibody, nr1h5.S antibody, nr1h4 antibody, NR1H4 antibody, Nr1h4 antibody
    背景
    NR1H4 is a Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
    分子量
    55914
    基因ID
    9971
    NCBI登录号
    NP_001193906, NP_001193907, NP_001193908, NP_001193921, NP_001193922, NP_005114
    UniProt
    Q96RI1
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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