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HLA-DMB 抗体 (AA 127-154)

HLA-DMB 适用: 人 WB 宿主: 兔 Polyclonal RB31771 unconjugated
产品编号 ABIN1537808
发货至: 中国
  • 抗原 See all HLA-DMB 抗体
    HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
    抗原表位
    • 12
    • 12
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 127-154
    适用
    • 42
    • 1
    宿主
    • 39
    • 3
    克隆类型
    • 38
    • 4
    多克隆
    标记
    • 22
    • 4
    • 4
    • 4
    • 4
    • 4
    This HLA-DMB antibody is un-conjugated
    应用范围
    • 41
    • 31
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HLA-DMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-154 amino acids from the Central region of human HLA-DMB.
    克隆位点
    RB31771
    亚型
    Ig Fraction
    Top Product
    Discover our top product HLA-DMB Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    HLA-DMB Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
    别名
    HLA-DMB (HLA-DMB 产品)
    别名
    RING7 antibody, D6S221E antibody, RT1.DMb antibody, RT1.Mb antibody, MHC-DMB antibody, major histocompatibility complex, class II, DM beta antibody, RT1 class II, locus DMb antibody, HLA-DMB antibody, RT1-DMb antibody, PATR-DMB antibody
    背景
    HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
    分子量
    28943
    基因ID
    3109
    NCBI登录号
    NP_002109
    UniProt
    P28068
    途径
    Cancer Immune Checkpoints
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