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IL-1 beta 抗体 (AA 148-174)

This anti-IL-1 beta antibody is a 小鼠 单克隆 antibody detecting IL-1 beta in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1537701
发货至: 中国

Quick Overview for IL-1 beta 抗体 (AA 148-174) (ABIN1537701)

抗原

See all IL-1 beta (IL1B) 抗体
IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-1 beta antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

614CT4-3-1
  • 抗原表位

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    AA 148-174

    预测反应

    Pr, Rb

    纯化方法

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    免疫原

    This IL1B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 148-174 amino acids from the Central region of human IL1B.

    亚型

    IgG1
  • 应用备注

    WB: 1:2000~4000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    IL1B Antibody (Center)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • Liu, Wang, Zou, Fan, Hu, Feng, Zhu, Xiong: "Monocyte chemoattractant protein 1 released from macrophages induced by hepatitis C virus promotes monocytes migration." in: Virus research, Vol. 240, pp. 190-196, (2018) (PubMed).

  • 抗原

    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

    别名

    IL1B

    背景

    The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq].

    分子量

    30748

    基因ID

    3553

    NCBI登录号

    NP_000567

    UniProt

    P01584

    途径

    NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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