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HLA-DPA1 抗体 (C-Term)

HLA-DPA1 适用: 人 WB 宿主: 兔 Polyclonal RB36729 unconjugated
产品编号 ABIN1536899
发货至: 中国
  • 抗原 See all HLA-DPA1 抗体
    HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1))
    抗原表位
    • 7
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    AA 231-259, C-Term
    适用
    • 37
    • 1
    • 1
    宿主
    • 34
    • 3
    克隆类型
    • 35
    • 2
    多克隆
    标记
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-DPA1 antibody is un-conjugated
    应用范围
    • 28
    • 22
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HLA-DPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-259 amino acids from the C-terminal region of human HLA-DPA1.
    克隆位点
    RB36729
    亚型
    Ig Fraction
    Top Product
    Discover our top product HLA-DPA1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    HLA-DPA1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1))
    别名
    HLA-DPA1 (HLA-DPA1 产品)
    别名
    DP(W3) antibody, DP(W4) antibody, HLA-DP1A antibody, HLADP antibody, HLASB antibody, PLT1 antibody, major histocompatibility complex, class II, DP alpha 1 antibody, HLA-DPA1 antibody
    背景
    HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
    分子量
    29381
    基因ID
    3113
    NCBI登录号
    NP_001229453, NP_001229454, NP_291032
    UniProt
    P20036
    途径
    TCR Signaling, Cancer Immune Checkpoints
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