HLA-DPA1 抗体
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- 抗原 See all HLA-DPA1 抗体
- HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HLA-DPA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human HLA-DPA1
- 亚型
- IgG
- Top Product
- Discover our top product HLA-DPA1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.96 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1))
- 别名
- HLA-DPA1 (HLA-DPA1 产品)
- 别名
- DP(W3) antibody, DP(W4) antibody, HLA-DP1A antibody, HLADP antibody, HLASB antibody, PLT1 antibody, major histocompatibility complex, class II, DP alpha 1 antibody, HLA-DPA1 antibody
- 背景
- HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 29 kDa
- UniProt
- P20036
- 途径
- TCR Signaling, Cancer Immune Checkpoints
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