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Actin 抗体

ACTA1 适用: 人 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 337CT30-10-1 unconjugated
产品编号 ABIN1536597
发货至: 中国
  • 抗原 See all Actin (ACTA1) 抗体
    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
    适用
    • 96
    • 44
    • 43
    • 17
    • 12
    • 10
    • 9
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    • 6
    • 6
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    • 5
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 81
    • 31
    小鼠
    克隆类型
    • 76
    • 34
    单克隆
    标记
    • 63
    • 12
    • 12
    • 10
    • 5
    • 4
    • 1
    • 1
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    This Actin antibody is un-conjugated
    应用范围
    • 91
    • 57
    • 40
    • 28
    • 27
    • 25
    • 10
    • 9
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    预测反应
    B, C, M, Pig, Rb, Rat
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This ACTA1 monoclonal antibody is generated from mouse immunized with ACTA1 recombinant protein.
    克隆位点
    337CT30-10-1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ACTA1 Primary Antibody
  • 应用备注
    WB: 1:500-1:1000. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    ACTA1 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Vuković, Jevtić, Zhang, Stohr, Levy: "Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding." in: Journal of cell science, Vol. 129, Issue 6, pp. 1115-27, (2017) (PubMed).

    Edens, Dilsaver, Levy: "PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cells." in: Molecular biology of the cell, Vol. 28, Issue 10, pp. 1389-1399, (2017) (PubMed).

  • 抗原
    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
    别名
    ACTA1 (ACTA1 产品)
    别名
    ACTA antibody, ASMA antibody, CFTD antibody, CFTD1 antibody, CFTDM antibody, MPFD antibody, NEM1 antibody, NEM2 antibody, NEM3 antibody, acta antibody, asma antibody, cftd antibody, cftd1 antibody, cftdm antibody, mpfd antibody, nem1 antibody, AA959943 antibody, Acta-2 antibody, Acts antibody, Actsk-1 antibody, actc antibody, actc1 antibody, cfk antibody, hm:zeh0631 antibody, zeh0631 antibody, acta1 antibody, hm:zeh0293 antibody, zgc:112098 antibody, actin, alpha 1, skeletal muscle antibody, actin, alpha 1, skeletal muscle L homeolog antibody, actin, alpha 1b, skeletal muscle antibody, actin, muscle antibody, actin, alpha skeletal muscle antibody, actin, alpha 1a, skeletal muscle antibody, ACTA1 antibody, acta1.L antibody, acta1 antibody, Acta1 antibody, acta1b antibody, LOC100533357 antibody, LOC109479779 antibody, LOC109108280 antibody, acta1a antibody
    背景
    The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
    分子量
    42051
    基因ID
    58
    NCBI登录号
    NP_001091
    UniProt
    P68133
    途径
    Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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