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Actin 抗体 (C-Term)

ACTA1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043519
发货至: 中国
  • 抗原 See all Actin (ACTA1) 抗体
    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
    抗原表位
    • 18
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 277-308, C-Term
    适用
    • 95
    • 43
    • 42
    • 17
    • 12
    • 10
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 80
    • 31
    克隆类型
    • 75
    • 34
    多克隆
    标记
    • 62
    • 12
    • 12
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Actin antibody is un-conjugated
    应用范围
    • 90
    • 57
    • 40
    • 28
    • 27
    • 24
    • 10
    • 9
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Actin, alpha skeletal muscle(ACTA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    HETTYNSIMK CDIDIRKDLY ANNVMSGGTT MY
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Actin, alpha skeletal muscle(ACTA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: actin, alpha 1, skeletal muscle
    Protein Name: Actin, alpha skeletal muscle
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Actin (277-308aa HETTYNSIMKCDIDIRKDLYANNVMSGGTTMY), identical to the related mouse and rat sequences.
    亚型
    IgG
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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    Yan, Chen, Gong, Yin, Zhou, Chaugai, Wang: "miR-21-3p regulates cardiac hypertrophic response by targeting histone deacetylase-8." in: Cardiovascular research, Vol. 105, Issue 3, pp. 340-52, (2015) (PubMed).

    Mitsuhashi, Shindo, Shigetomi, Miyamoto, Ubukata: "(+)-Epogymnolactam, a novel autophagy inducer from mycelial culture of Gymnopus sp." in: Phytochemistry, Vol. 114, pp. 163-7, (2015) (PubMed).

    Wu, Sun, Wu, Li, Du, Zeng, Bi, Sun: "Activation of calcium-sensing receptor increases TRPC3/6 expression in T lymphocyte in sepsis." in: Molecular immunology, Vol. 64, Issue 1, pp. 18-25, (2015) (PubMed).

    Hong, Zhang, Zhang, Yang, Wan, Yu, Wang, Feng, Li, Yew: "Expression of dopamine transporter in the different cerebral regions of methamphetamine-dependent rats." in: Human & experimental toxicology, Vol. 34, Issue 7, pp. 707-17, (2015) (PubMed).

    Xie, Zhang, Chen, Pan, Wu, Ge, Yang: "Effects of ghrelin on postresuscitation brain injury in a rat model of cardiac arrest." in: Shock (Augusta, Ga.), Vol. 43, Issue 5, pp. 490-6, (2015) (PubMed).

    Dai, Yin, Zhao, Guo, Li, Ma, Lu: "III-10, a newly synthesized flavonoid, induces cell apoptosis with the involvement of reactive oxygen species-mitochondria pathway in human hepatocellular carcinoma cells." in: European journal of pharmacology, Vol. 764, pp. 353-62, (2015) (PubMed).

    Cheng, Ji, Liu, Mei, Wang, Feng, Ding: "Erratum: Expression changes of ionic channels in early phase of cultured rat atrial myocytes induced by rapid pacing." in: Journal of cardiothoracic surgery, Vol. 10, pp. 10, (2015) (PubMed).

    Liu, Wang, Wang, Wang: "Anticancer effects of chemokine receptor 4(CXCR4) gene silenced by CXCR4-siRNA in nude mice model of ovarian cancer." in: Cell biochemistry and biophysics, Vol. 70, Issue 3, pp. 1893-900, (2014) (PubMed).

    Chen, Yang, Pang, Peng, Dong, Liu, Ouyang, Ren: "Expression, purification and antibody preparation using different constructs of PCV2 capsid protein." in: International journal of biological macromolecules, Vol. 67, pp. 289-94, (2014) (PubMed).

    Gong, Liu, Ding, Liu, Li, Zheng, Jia, Zhou, Zou, Li, Huang, Fan: "Physiological pulsatile flow culture conditions to generate functional endothelium on a sulfated silk fibroin nanofibrous scaffold." in: Biomaterials, Vol. 35, Issue 17, pp. 4782-91, (2014) (PubMed).

    Tao, Fu, Wang, Yao, Zhou, Dai, Li, Lu, Wang: "LL-202, a newly synthesized flavonoid, inhibits tumor growth via inducing G(2)/M phase arrest and cell apoptosis in MCF-7 human breast cancer cells in vitro and in vivo." in: Toxicology letters, Vol. 228, Issue 1, pp. 1-12, (2014) (PubMed).

    Li, Chen, Ouyang, Chen, Wu, Kuang, Zheng: "Increased autophagy sustains the survival and pro-tumourigenic effects of neutrophils in human hepatocellular carcinoma." in: Journal of hepatology, Vol. 62, Issue 1, pp. 131-9, (2014) (PubMed).

    Zhou, Wang, Tokunaga, Huang, Sun, Yang: "The HIV-1 accessory protein Vpr induces the degradation of the anti-HIV-1 agent APOBEC3G through a VprBP-mediated proteasomal pathway." in: Virus research, Vol. 195, pp. 25-34, (2014) (PubMed).

    Tang, Liu, Yang, Xie, Ye, Wu, Liu, Chen, Zhang, Xie: "miR-185 suppresses tumor proliferation by directly targeting E2F6 and DNMT1 and indirectly upregulating BRCA1 in triple-negative breast cancer." in: Molecular cancer therapeutics, Vol. 13, Issue 12, pp. 3185-97, (2014) (PubMed).

    Cheng, Zhao, Wang, Lu, Wang, Wang, Yao: "The effect of 5'-adenylic acid on hepatic proteome of mice radiated by 60Co γ-ray." in: International journal of molecular sciences, Vol. 15, Issue 1, pp. 186-202, (2014) (PubMed).

    Li, Chen, Li, Zhang, Tang: "Cytotoxicity of polyaniline nanomaterial on rat celiac macrophages in vitro." in: PLoS ONE, Vol. 9, Issue 9, pp. e107361, (2014) (PubMed).

    Li, Shang: "Inhaled corticosteroids inhibit substance P receptor expression in asthmatic rat airway smooth muscle cells." in: BMC pulmonary medicine, Vol. 12, pp. 79, (2013) (PubMed).

    Yu, Dai, Chen, Zang, Deng, Liu, Ying: "Hypolipidemic and antioxidant activities of polysaccharides from Rosae Laevigatae Fructus in rats." in: Carbohydrate polymers, Vol. 94, Issue 1, pp. 56-62, (2013) (PubMed).

    Leng, Wang, Pang, Zhan, Zhang, Wang, Gao, Qian: "Evidence of a role for both anti-Hsp70 antibody and endothelial surface membrane Hsp70 in atherosclerosis." in: Cell stress & chaperones, Vol. 18, Issue 4, pp. 483-93, (2013) (PubMed).

  • 抗原
    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
    别名
    ACTA1 (ACTA1 产品)
    别名
    ACTA antibody, ASMA antibody, CFTD antibody, CFTD1 antibody, CFTDM antibody, MPFD antibody, NEM1 antibody, NEM2 antibody, NEM3 antibody, acta antibody, asma antibody, cftd antibody, cftd1 antibody, cftdm antibody, mpfd antibody, nem1 antibody, AA959943 antibody, Acta-2 antibody, Acts antibody, Actsk-1 antibody, actc antibody, actc1 antibody, cfk antibody, hm:zeh0631 antibody, zeh0631 antibody, acta1 antibody, hm:zeh0293 antibody, zgc:112098 antibody, actin, alpha 1, skeletal muscle antibody, actin, alpha 1, skeletal muscle L homeolog antibody, actin, alpha 1b, skeletal muscle antibody, actin, muscle antibody, actin, alpha skeletal muscle antibody, actin, alpha 1a, skeletal muscle antibody, ACTA1 antibody, acta1.L antibody, acta1 antibody, Acta1 antibody, acta1b antibody, LOC100533357 antibody, LOC109479779 antibody, LOC109108280 antibody, acta1a antibody
    背景
    Actin, a highly conserved protein, is a major component of both the cytoskeletal and contractile structures in the cell types. It varies in amount, being related to the type of differentiation and to the functional state of cells and tissues. The actins exhibit over 90 % sequence homology, but each isoform has a unique NH2-terminal sequence. The isoforms are comprised of three alpha-actin, one beta-actin, two gamma-actin. Because the amino acid sequence of the C-terminal is the same for almost all actins, this antibody has been raised using a synthetic peptide corresponding to the C-terminal 11 residues.

    Synonyms: ACTA antibody|ACTA1 antibody|Actin alpha skeletal muscle antibody|Actin antibody|actin, alpha 1, skeletal muscle 1 antibody|actin, alpha 1, skeletal muscle antibody|Actin, alpha skeletal muscle antibody|actina antibody|actine antibody|ACTS_HUMAN antibody|aktin antibody|Alpha Actin 1 antibody|Alpha skeletal muscle Actin antibody|alpha skeletal muscle antibody|alpha-actin antibody|Alpha-actin-1 antibody|ASMA antibody|CFTD antibody|CFTD1antibody|CFTDM antibody|MPFD antibody|NEM1 antibody|NEM2 antibody|NEM3 antibody|nemaline myopathy type 3 antibody
    基因ID
    58
    UniProt
    P68133
    途径
    Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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