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Actin 抗体 (C-Term)

ACTA1 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB35391 unconjugated
产品编号 ABIN658563
发货至: 中国
  • 抗原 See all Actin (ACTA1) 抗体
    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
    抗原表位
    • 18
    • 9
    • 7
    • 7
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 346-375, C-Term
    适用
    • 95
    • 44
    • 43
    • 17
    • 12
    • 10
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 80
    • 31
    克隆类型
    • 75
    • 34
    多克隆
    标记
    • 62
    • 12
    • 12
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Actin antibody is un-conjugated
    应用范围
    • 90
    • 57
    • 40
    • 27
    • 26
    • 24
    • 10
    • 9
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)
    特异性
    This ACTA1/?-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-376 amino acids from the C-terminal region of human ACTA1/?-actin.
    预测反应
    Cow (Bovine),Chicken,Mouse (Murine),Pig (Porcine),Rat (Rattus),Rabbit,Xenopus laevis
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This ACTA1/Alpha-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 AA from the C-terminal region of human ACTA1/Alpha-actin.
    克隆位点
    RB35391
    亚型
    Ig Fraction
    Top Product
    Discover our top product ACTA1 Primary Antibody
  • 应用备注
    WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Xiao, Gao, Gao, Zhao, Hong, Li, Yao, Cheng, Zhou: "Directed Differentiation of Zebrafish Pluripotent Embryonic Cells to Functional Cardiomyocytes." in: Stem cell reports, Vol. 7, Issue 3, pp. 370-382, (2017) (PubMed).

    Ying, Xie, Bai, Chen, Wang, Zhang, Morishita, Sun, Rajagopalan: "Exposure to concentrated ambient particulate matter induces reversible increase of heart weight in spontaneously hypertensive rats." in: Particle and fibre toxicology, Vol. 12, Issue 1, pp. 15, (2015) (PubMed).

  • 抗原
    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
    Abstract
    ACTA1 产品
    别名
    ACTA antibody, ASMA antibody, CFTD antibody, CFTD1 antibody, CFTDM antibody, MPFD antibody, NEM1 antibody, NEM2 antibody, NEM3 antibody, acta antibody, asma antibody, cftd antibody, cftd1 antibody, cftdm antibody, mpfd antibody, nem1 antibody, AA959943 antibody, Acta-2 antibody, Acts antibody, Actsk-1 antibody, actc antibody, actc1 antibody, cfk antibody, hm:zeh0631 antibody, zeh0631 antibody, acta1 antibody, hm:zeh0293 antibody, zgc:112098 antibody, actin, alpha 1, skeletal muscle antibody, actin, alpha 1, skeletal muscle L homeolog antibody, actin, alpha 1b, skeletal muscle antibody, actin, muscle antibody, actin, alpha skeletal muscle antibody, actin, alpha 1a, skeletal muscle antibody, ACTA1 antibody, acta1.L antibody, acta1 antibody, Acta1 antibody, acta1b antibody, LOC100533357 antibody, LOC109479779 antibody, LOC109108280 antibody, acta1a antibody
    背景
    The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
    Synonyms: Actin, alpha skeletal muscle,ACTA1,ACTA
    分子量
    42051 Da
    基因ID
    58
    UniProt
    P68133
    途径
    Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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