C-JUN 抗体 (pThr231)
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北京 101111
Quick Overview for C-JUN 抗体 (pThr231) (ABIN1531557)
抗原
See all C-JUN (JUN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-250, pThr231
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原理
- AP-1 (phospho Thr231) Antibody
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特异性
- Phospho-AP-1 (T231) Polyclonal Antibody detects endogenous levels of AP-1 protein only when phosphorylated at T231.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human c-Jun around the phosphorylation site of Thr231. AA range:201-250
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- C-JUN (JUN) (Jun Proto-Oncogene (JUN))
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别名
- C-Jun
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背景
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Synonyms: JUN, Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39
Background: This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008],
Gene Name: JUN
Protein Name: Transcription factor AP-1, jun, c-jun,AP-1
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分子量
- 35 kDa
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基因ID
- 3725
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OMIM
- 165160
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UniProt
- P05412
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途径
- MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
抗原
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