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Nephrin 抗体 (Middle Region)

NPHS1 适用: 人 IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1450160
发货至: 中国
  • 抗原 See all Nephrin (NPHS1) 抗体
    Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
    抗原表位
    • 14
    • 8
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    • 7
    • 5
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    • 3
    • 2
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    Middle Region
    适用
    • 80
    • 49
    • 28
    • 15
    宿主
    • 82
    • 5
    • 2
    • 1
    克隆类型
    • 81
    • 9
    多克隆
    标记
    • 38
    • 10
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    • 3
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    • 3
    • 3
    • 2
    • 1
    • 1
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    This Nephrin antibody is un-conjugated
    应用范围
    • 39
    • 37
    • 19
    • 18
    • 16
    • 11
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    16 amino acid synthetic peptide from near the center of human Nephrin
    亚型
    IgG
    Top Product
    Discover our top product NPHS1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
    别名
    Nephrin (NPHS1 产品)
    别名
    NPHS1 antibody, nphs1l antibody, nphs1 antibody, CNF antibody, NPHN antibody, nephrin antibody, NephrinB antibody, NPHS1, nephrin antibody, nephrosis 1, congenital, Finnish type (nephrin) antibody, NPHS1 nephrin S homeolog antibody, nephrin antibody, NPHS1 nephrin antibody, nephrosis 1, nephrin antibody, NPHS1 antibody, nphs1 antibody, nphs1.S antibody, LOC5579127 antibody, Nphs1 antibody
    背景
    Nephrin is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth. Renal glomeruli allow normal kidneys to filter plasma so that it is very pure. Nephrin is expressed in the podocyte slit-diaphragm of the renal glomeruli in a manner that suggests that Nephrin molecules homodimerize in an anti-parallel fashion similar to cadherin interactions in adherens junctions. Thus, Nephrin may constitute the entire extracellular structure of the slit-diaphragm.Synonyms: NPHN, NPHS1
    基因ID
    4868
    NCBI登录号
    NP_004637
    途径
    Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development
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