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p53 抗体 (pSer20)

TP53 适用: 人 WB 宿主: 小鼠 Monoclonal 17B6 unconjugated
产品编号 ABIN1449251
发货至: 中国
  • 抗原 See all p53 (TP53) 抗体
    p53 (TP53) (Tumor Protein P53 (TP53))
    抗原表位
    • 50
    • 40
    • 39
    • 38
    • 32
    • 28
    • 26
    • 24
    • 23
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    pSer20
    适用
    • 869
    • 267
    • 219
    • 110
    • 45
    • 34
    • 31
    • 18
    • 10
    • 8
    • 8
    • 6
    • 4
    • 4
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 663
    • 220
    • 6
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 611
    • 281
    • 1
    单克隆
    标记
    • 493
    • 49
    • 36
    • 26
    • 25
    • 24
    • 24
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This p53 antibody is un-conjugated
    应用范围
    • 704
    • 328
    • 247
    • 216
    • 199
    • 144
    • 124
    • 119
    • 117
    • 61
    • 56
    • 32
    • 20
    • 17
    • 13
    • 12
    • 12
    • 10
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    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts with the human phosphorylated p53 (Ser20).
    克隆位点
    17B6
    亚型
    IgG1
    Top Product
    Discover our top product TP53 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    50 μg IgG in 50 μL volume of PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Azide free
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    p53 (TP53) (Tumor Protein P53 (TP53))
    别名
    p53 (TP53) (TP53 产品)
    别名
    BCC7 antibody, LFS1 antibody, P53 antibody, TRP53 antibody, p53 antibody, Trp53 antibody, brp53 antibody, drp53 antibody, etID22686.5 antibody, fb40d06 antibody, wu:fb40d06 antibody, zgc:111919 antibody, Tp53 antibody, bbl antibody, bfy antibody, bhy antibody, p44 antibody, tp53 antibody, Xp53 antibody, TP53 antibody, tumor protein p53 antibody, cellular tumor antigen p53 antibody, transformation related protein 53 antibody, tumor protein p53 L homeolog antibody, TP53 antibody, CpipJ_CPIJ002758 antibody, Tp53 antibody, tp53 antibody, Trp53 antibody, tp53.L antibody
    背景
    P53 mutants are found in more than half of human cancers and ar e considered as the most important human cancer related gene. p53 is detected at 53 kDa position by electrophoresis and is composed of 393 amino acids. In the unstressed normal cells the p53 level is low and it is inactive. However, with stress, especially with DNA damage, it is activated to promote arrest of cell cycle and repair of DNA damage, or induction of apoptosis. The functions of p53 are regulated by the phosphorylation of serine and threonine, and th e acetylation of lysine at various sites in the molecule (Ref 1). p53 at Ser20 is phosphorylated by Chk1 and Chk2 kinases and this enhances tetramerization, stability and activity of p53 (Ref 2,3)Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
    基因ID
    7157
    NCBI登录号
    NP_000537
    UniProt
    P04637
    途径
    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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