SPO11 抗体 (Alexa Fluor 555)
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- 抗原 See all SPO11 抗体
- SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPO11 antibody is conjugated to Alexa Fluor 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SPO11
- 亚型
- IgG
- Top Product
- Discover our top product SPO11 Primary Antibody
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anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 291-395) antibody
SPO11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 1-358) antibodySPO11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 28-109) antibodySPO11 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 1-358) antibodySPO11 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (Internal Region) antibodyVerified SPO11 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 110-159) antibodySPO11 适用: 人, 斑马鱼, Cow, 犬, 豚鼠, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (N-Term) antibodySPO11 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
- 别名
- SPO11 (SPO11 产品)
- 别名
- CT35 antibody, SPATA43 antibody, TOPVIA antibody, zgc:77876 antibody, AI449549 antibody, Meiotic recombination protein spo-11 antibody, SPO11, initiator of meiotic double stranded breaks antibody, SPO11 meiotic protein covalently bound to DSB antibody, spo-11 antibody, SPO11 antibody, Spo11 antibody, spo11 antibody
- 背景
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Synonyms: Meiotic recombination protein SPO 11, Meiotic recombination protein SPO11, MGC39953, SPO 11, SPO11 meiotic protein covalently bound to DSB homolog, SPO11 meiotic protein covalently bound to DSB like, SPO11_HUMAN.
Background: Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination. The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S. cerevisiae. The DSBs are located mostly in promoter regions, where the chromatin is in an open configuration, and cluster in domains along the chromosome. Expression of the Spo11 is detected mainly in the testis, in agreement with its predicted function in the initiation of meiotic recombination. Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility.
- 基因ID
- 23626
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