SPO11 抗体 (N-Term)
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北京 101111
Quick Overview for SPO11 抗体 (N-Term) (ABIN2785945)
抗原
See all SPO11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- SPO11 Antibody - N-terminal region
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序列
- KFSLILKILS MIYKLVQSNT YATKRDIYYT DSQLFGNQTV VDNIINDISC
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against SPO11. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SPO11
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anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 291-395) antibody
SPO11 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 1-358) antibodySPO11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (Internal Region) antibodyVerified SPO11 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 299-326), (C-Term) antibodySPO11 适用: 人 WB 宿主: 兔 Polyclonal RB37642 unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 110-159) antibodySPO11 适用: 人, Cow, 犬, 豚鼠, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 28-109) antibodySPO11 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 1-358) antibodySPO11 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54901-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
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别名
- SPO11
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背景
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Background Information: Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. SPO11 is similar in sequence and conserved features to the yeast meiotic recombination protein. It belongs to the TOP6A protein family. Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
Gene Name: SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
Alternative Symbols: CT35, TOPVIA, SPATA43, TOPOVIA
Protein Name: Meiotic recombination protein SPO11
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分子量
- 44kDa
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基因ID
- 23626
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NCBI登录号
- NP_036576
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UniProt
- Q9Y5K1
抗原
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