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SPO11 产品

(SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

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Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008].

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Featured SPO11 Categories

SPO11 抗体

High quality antibodies with extensive validation data.

SPO11 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPO11 抗体

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Reactivity
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Datasheet
Reactivity Human
Application WB, ELISA
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Cat. No. ABIN525320
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
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Cat. No. ABIN525322
Quantity 100 μg
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Reactivity Human
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Cat. No. ABIN7159201
Quantity 100 μg
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Recommended SPO11 ELISA试剂盒

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Reactivity
Analytical Method
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Cat. No.
Quantity
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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6232461
Quantity 96 tests
Datasheet Datasheet

Recommended SPO11 蛋白

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Reactivity
Source
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Cat. No. ABIN1321209
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1321211
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Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3077536
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Latest Publications for our SPO11 Products

Suberbielle, Sanchez, Kravitz, Wang, Ho, Eilertson, Devidze, Kreitzer, Mucke: "Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β." in: Nature neuroscience, Vol. 16, Issue 5, pp. 613-21, (2013) (PubMed).

Synonyms and alternative names related to SPO11

Meiotic recombination protein spo-11 (spo-11), SPO11, initiator of meiotic double stranded breaks (SPO11), SPO11, initiator of meiotic double stranded breaks (Spo11), SPO11 meiotic protein covalently bound to DSB (spo11), SPO11 meiotic protein covalently bound to DSB (Spo11), AI449549, CT35, SPATA43, TOPVIA, zgc:77876

Protein level used designations for SPO11

  • SPO11 meiotic protein covalently bound to DSB homolog
  • cancer/testis antigen 35
  • meiotic recombination protein SPO11
  • spermatogenesis associated 43
  • sporulation protein, meiosis-specific, SPO11 homolog
  • sporulation protein, meiosis-specific, SPO11
  • sporulation protein, meiosis-specific, SPO11 homolog (S. cervisiae)
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