F4/80 抗体 (AA 732-747) (Biotin)
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- 抗原 See all F4/80 (EMR1) 抗体
- F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
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抗原表位
- AA 732-747
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适用
- 小鼠, 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This F4/80 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EMR1
- 亚型
- IgG
- Top Product
- Discover our top product EMR1 Primary Antibody
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anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 732-747) antibody
EMR1 适用: 小鼠, 人, 大鼠 FACS, WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 21-290) antibodyEMR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (C-Term) antibodyEMR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 1-201) antibodyEMR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (C-Term) antibodyEMR1 适用: 小鼠, 人, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) antibody (PE)EMR1 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal BM8-1 PE
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 21-290) antibodyEMR1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 1-821) antibodyEMR1 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) antibodyEMR1 适用: 小鼠 FACS, WB, IHC (p) 宿主: 大鼠 Monoclonal BM8 unconjugated
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) antibody (FITC)EMR1 适用: 小鼠 FACS, WB, IHC (p) 宿主: 大鼠 Monoclonal BM8 FITC
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- 应用备注
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WB 1:100-1000
IHC-P 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
- 别名
- Emr1 (EMR1 产品)
- 别名
- EMR1 antibody, TM7LN3 antibody, DD7A5-7 antibody, EGF-TM7 antibody, F4/80 antibody, Gpf480 antibody, Ly71 antibody, adhesion G protein-coupled receptor E1 antibody, ADGRE1 antibody, LOC100424335 antibody, Adgre1 antibody
- 背景
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Synonyms: TM7LN3, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, EMR1 hormone receptor, EMR1, Adhesion G Protein-Coupled Receptor E1, ADGRE1, Cell surface glycoprotein F4/80
Background: The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (13). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (13). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 Molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages.
- 基因ID
- 2015
- UniProt
- Q14246
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