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F4/80 抗体 (AA 732-747)

Name: F4/80 抗体 (AA 732-747)
SKU: ABIN1387314
Availability: OutOfStock

EMR1 适用: 小鼠, 人, 大鼠 FACS, WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated

Mouse splenocytes probed with Rabbit Anti-EMR1 Polyclonal Antibody, Unconjugated .

FACS

Formalin-fixed and paraffin embedded human breast carcinoma labeled with Rabbit Anti EMR1 Polyclonal Antibody, Unconjugated (ABIN1387314) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti EMR1 Polyclonal Antibody, Unconjugated (ABIN1387314) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti-EMR1 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

4 images

(3 references)

产品编号 ABIN1387314

发货至: 中国

Datasheet as PDF

抗原 See all F4/80 (EMR1) 抗体

F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
抗原表位
14

7

7

3

3

2

2

2

2

1

1

1

1

1
AA 732-747
适用
91

51

29

4

4

1
小鼠, 人, 大鼠
宿主
55

46

4

3

2

1
兔
Compatible Secondaries
克隆类型
55

48

2
多克隆
标记
42

10

9

8

4

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This F4/80 antibody is un-conjugated
应用范围
79

55

24

17

13

12

12

11

11

6

6

3

2

2

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human EMR1

亚型

IgG
anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 21-290) antibody
EMR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (C-Term) antibody
EMR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 1-201) antibody
EMR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (C-Term) antibody
EMR1 适用: 小鼠, 人, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) antibody (PE)
EMR1 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal BM8-1 PE

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 21-290) antibody
EMR1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 1-821) antibody
EMR1 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) antibody
EMR1 适用: 小鼠 FACS, WB, IHC (p) 宿主: 大鼠 Monoclonal BM8 unconjugated

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) antibody (FITC)
EMR1 适用: 小鼠 FACS, WB, IHC (p) 宿主: 大鼠 Monoclonal BM8 FITC

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) (AA 626-886) antibody
EMR1 适用: 小鼠, 人, 大鼠, 犬 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C for 12 months.

有效期

12 months
Xue, Han, Ma, Wu, Qin, Liu, Hu, Hong, Hou: "Effect of Microenvironment on Differentiation of Human Umbilical Cord Mesenchymal Stem Cells into Hepatocytes In Vitro and In Vivo." in: BioMed research international, Vol. 2016, pp. 8916534, (2016) (PubMed).

Tsang, Huang, Yang, Chi, Chiang, Wang, Andocs, Szasz, Li, Chi: "Improving immunological tumor microenvironment using electro-hyperthermia followed by dendritic cell immunotherapy." in: BMC cancer, Vol. 15, pp. 708, (2015) (PubMed).

Kwan, Yeung, Liu, Wong, Shum, Lam, Cheng, Cheung, To: "Silver nanoparticles alter proteoglycan expression in the promotion of tendon repair." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1375-83, (2014) (PubMed).
抗原

F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))

别名

Emr1 (EMR1 产品)

别名

EMR1 antibody, TM7LN3 antibody, DD7A5-7 antibody, EGF-TM7 antibody, F4/80 antibody, Gpf480 antibody, Ly71 antibody, adhesion G protein-coupled receptor E1 antibody, ADGRE1 antibody, LOC100424335 antibody, Adgre1 antibody

背景

Synonyms: TM7LN3, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, EMR1 hormone receptor, EMR1, Adhesion G Protein-Coupled Receptor E1, ADGRE1, Cell surface glycoprotein F4/80
Background: The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (13). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (13). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 Molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages.

基因ID

2015

UniProt

Q14246