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CD40 抗体

CD40 适用: 人 FACS, IHC, Func 宿主: 小鼠 Monoclonal B-B20 unconjugated
产品编号 ABIN1383854
发货至: 中国
  • 抗原 See all CD40 抗体
    CD40
    适用
    • 188
    • 97
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    宿主
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    小鼠
    克隆类型
    • 156
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    单克隆
    标记
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    This CD40 antibody is un-conjugated
    应用范围
    • 145
    • 92
    • 62
    • 50
    • 30
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)
    特异性
    Recognises the Bp50 antigen, a 48 kDa protein
    纯化方法
    Ion exchange chromatography
    过滤
    0.22 μm filtered
    免疫原
    Raji cell line,Myeloma X63/AG.8653 x Balb/c spleen cells
    克隆位点
    B-B20
    亚型
    IgG1 kappa
    Biological Activity Comment
    Stimulates B-cell proliferation together with IL-4
    Top Product
    Discover our top product CD40 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • de Goër de Herve, Durali, Tran, Maigné, Simonetta, Leclerc, Delfraissy, Taoufik: "Differential effect of agonistic anti-CD40 on human mature and immature dendritic cells: the Janus face of anti-CD40." in: Blood, Vol. 106, Issue 8, pp. 2806-14, (2005) (PubMed).

    Durali, de Goër de Herve, Giron-Michel, Azzarone, Delfraissy, Taoufik: "In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment." in: Blood, Vol. 102, Issue 12, pp. 4084-9, (2003) (PubMed).

    Puig-Kröger, Relloso, Fernández-Capetillo, Zubiaga, Silva, Bernabéu, Corbí: "Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells." in: Blood, Vol. 98, Issue 7, pp. 2175-82, (2001) (PubMed).

    Jeannin, Delneste, Lecoanet-Henchoz, Gauchat, Ellis, Bonnefoy: "CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells." in: The Journal of biological chemistry, Vol. 272, Issue 25, pp. 15613-9, (1997) (PubMed).

  • 抗原
    CD40
    别名
    CD40 (CD40 产品)
    别名
    Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody
    分子量
    48 kDa
    途径
    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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